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CAS NO:
20736-08-7
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Basic Info
CAS Number
20736-08-7
Pharmacopoeia
In-house Standards
Grade
Pharmaceutical Grade
Is Manufacturer
No
Product Description
please call me ,to know more
AI Product Description
*The following content is generated by AI and is for reference only.
Saikosaponin C is a bioactive triterpenoid saponin primarily isolated from the roots of Bupleurum species, most notably *Bupleurum chinense* and *Bupleurum scorzonerifolium*. These plants have been utilized for centuries in traditional Chinese medicine to treat fever, liver disorders, and respiratory ailments. The chemical identity of Saikosaponin C is defined by its molecular formula, C42H68O13, and it is assigned the CAS Registry Number 579-20-8. Structurally, it belongs to the oleanane-type triterpenoids, characterized by a complex glycosidic structure where sugar moieties are attached to an aglycone core, which contributes significantly to its solubility and biological activity.
In modern pharmaceutical research and development, Saikosaponin C has garnered substantial attention for its diverse pharmacological properties. It exhibits potent anti-inflammatory effects by inhibiting key signaling pathways such as NF-κB, thereby reducing the production of pro-inflammatory cytokines. Furthermore, extensive studies suggest its hepatoprotective capabilities, offering protection against liver injury induced by toxins like carbon tetrachloride or alcohol through the modulation of oxidative stress markers and apoptosis-related proteins. Beyond liver health, emerging evidence points to potential anti-tumor activities, where Saikosaponin C may induce cell cycle arrest and promote apoptosis in various cancer cell lines without causing significant toxicity to normal cells. Additionally, it demonstrates immunomodulatory effects, helping to regulate immune responses in autoimmune conditions.
Due to these multifaceted benefits, Saikosaponin C serves as a critical standard reference material in quality control for herbal medicines containing Bupleurum extracts. It is also widely used as a lead compound in drug discovery programs aiming to develop novel therapeutic agents for chronic inflammatory diseases, liver fibrosis, and oncology. As a natural product, it offers a safer alternative with fewer side effects compared to many synthetic drugs, making it highly valuable for both academic research and commercial applications in the nutraceutical and pharmaceutical industries. Its isolation and purification continue to be optimized to ensure high purity for clinical trials and functional food supplements.
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