Product Description
Protirelin API Pharmaceutical Polypeptide supplier made in china 24305-27-9
AI Product Description
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Protirelin, chemically known as Thyrotropin-Releasing Hormone (TRH), is a critical tripeptide pharmaceutical polypeptide synthesized in China for global research and diagnostic applications. With the molecular formula C16H23N5O5 and a molecular weight of approximately 349.38 g/mol, this compound serves as the endogenous regulator of thyroid-stimulating hormone (TSH) release from the anterior pituitary gland. Its primary biological function involves stimulating the secretion of TSH and prolactin, making it an essential tool in neuroendocrine studies and clinical diagnostics.
The standard CAS number for Protirelin is 378-40-9. As a synthetic analog of the native hormone, it exhibits high stability and specificity, allowing researchers to investigate hypothalamic-pituitary-thyroid axis mechanisms without interference from natural degradation pathways. In pharmaceutical manufacturing, particularly within Chinese facilities specializing in peptide synthesis, Protirelin API is produced using advanced solid-phase peptide synthesis (SPPS) techniques to ensure exceptional purity levels, often exceeding 98% or 99%. These high-grade APIs are utilized by international laboratories for developing diagnostic kits, evaluating thyroid dysfunction disorders such as hypothyroidism, and conducting pharmacological screening for potential neurological therapies.
Beyond its diagnostic utility, Protirelin has been explored in therapeutic contexts for conditions involving dopamine antagonism and certain types of spinal cord injuries, although its clinical use remains largely confined to research settings. The availability of cost-effective, high-quality Protirelin from Chinese suppliers supports the global scientific community in advancing endocrinology and neuroscience research. Researchers rely on these consistent supplies to validate experimental models, ensuring reproducibility in studies regarding metabolic regulation and neural signaling. Whether used for ELISA assay development or receptor binding studies, Protirelin remains a cornerstone molecule in understanding hormonal feedback loops. Its precise chemical structure and reliable performance make it indispensable for both academic institutions and commercial biotechnology firms seeking robust solutions for thyroid-related investigations and broader neuroendocrine profiling.