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<h3>Overview</h3>
<p>Omadacycline tosylate is a semisynthetic aminomethylcycline antibiotic used for treating bacterial infections. Its core synthesis involves modifying tetracycline scaffolds with <strong>dimethylamino</strong> and <strong>tosylate</strong> groups to enhance stability and bioavailability. The molecular formula is C<sub>29</sub>H<sub>34</sub>N<sub>6</sub>O<sub>8</sub>S, with CAS number 1790592-58-1.</p>
<h3>Application</h3>
<ul>
<li><strong>Infectious Disease Therapy:</strong> Treatment of community-acquired bacterial pneumonia (CABP).</li>
<li><strong>Acute Bacterial Skin Infections:</strong> Management of acute bacterial skin and skin structure infections (ABSSSI).</li>
<li><strong>Antimicrobial Stewardship:</strong> Alternative for multidrug-resistant Gram-positive pathogens.</li>
</ul>
<h3>Precautions</h3>
<p>Contraindicated in patients with hypersensitivity to cyclines. Avoid use during pregnancy due to potential fetal harm. Store powder at controlled room temperature (20°C–25°C) in dry conditions to prevent hydrolysis.</p>