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<h3>Overview</h3>
<p><strong>Nilotinib hydrochloride monohydrate</strong> is a third-generation tyrosine kinase inhibitor synthesized via condensation and salt formation. It serves as a critical research reagent for oncology studies targeting BCR-ABL1 mutations. Molecular Formula: C24H27ClN8O·HCl·H2O; CAS No.: 656240-98-5.</p>
<h3>Application</h3>
<ul>
<li><strong>In Vitro Research:</strong> Screening efficacy against imatinib-resistant leukemia cell lines.</li>
<li><strong>Drug Discovery:</strong> Developing novel formulations for chronic myeloid leukemia (CML).</li>
<li><strong>Pharmacokinetics:</strong> Studying metabolic pathways and bioavailability in preclinical models.</li>
</ul>
<h3>Precautions</h3>
<p>Strictly designated for laboratory use only, not for human or animal clinical administration. Store under inert atmosphere at -20°C to prevent hydrolysis. Personnel must utilize appropriate PPE due to potential cytotoxicity.</p>