Product Description
| Niacinamide |
| MFCD00006395 |
| Nicotinic acid amide |
| Vitamin- B3 |
| Witamina PP |
| 3-Pyridinecarboxamide |
| Nicotinamide |
| Pyridine-3-carboxamide |
| T6NJ CVZ |
| Dipigyl |
| EINECS 202-713-4 |
| Vi-noctyl |
AI Product Description
*The following content is generated by AI and is for reference only.
Nicotinamide, also known as niacinamide or vitamin B3, is a water-soluble organic compound essential for human health and widely utilized across pharmaceutical, cosmetic, and industrial sectors. Its molecular formula is C6H6N2O, and it carries the CAS Registry Number 98-92-0. Structurally, it consists of a pyridine ring substituted with an amide group at the fourth position, making it a stable derivative of nicotinic acid that does not cause the flushing reaction often associated with its parent compound.
In the biological realm, nicotinamide serves as a precursor to vital coenzymes, specifically NAD+ (nicotinamide adenine dinucleotide) and NADP+. These coenzymes are fundamental to cellular metabolism, facilitating redox reactions involved in energy production, DNA repair, and cell signaling pathways. Consequently, it is a critical dietary supplement used to prevent and treat pellagra, a disease caused by severe niacin deficiency, characterized by dermatitis, diarrhea, and dementia. Beyond nutrition, it plays a significant role in maintaining skin integrity. In the cosmetics industry, nicotinamide is a star ingredient found in serums, creams, and lotions due to its multifaceted benefits. It helps strengthen the skin barrier, reduces inflammation, minimizes pore appearance, and inhibits melanosome transfer to lighten hyperpigmentation and even out skin tone. Furthermore, it possesses antioxidant properties that protect against environmental stressors like UV radiation and pollution.
Industrially, it finds applications in chemical synthesis as a building block for various heterocyclic compounds and pharmaceuticals. Its stability under varying pH levels and temperatures makes it versatile for formulation. While generally recognized as safe for consumption and topical application, high doses may occasionally cause gastrointestinal discomfort or liver toxicity, necessitating adherence to recommended guidelines. Overall, Nicotinamide stands as a cornerstone molecule bridging nutritional science, dermatology, and chemical manufacturing, offering profound benefits for both internal physiology and external aesthetics through its unique ability to support cellular function and skin health.
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