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Intermediates&Fine Chemicals

Naproxen

Category:

Intermediates&Fine Chemicals

CAS NO:

22204-53-1

Standard:

In-house Standards,

Price Range:

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Main Sales Markets:

North America,Central/South America,Western Europe,Eastern Europe,Australasia,Asia,Middle East,Africa

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INNER MONGOLIA YUANHONG FINE CHEMICAL CO., LTD.

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Basic Info

CAS Number

22204-53-1

Pharmacopoeia

In-house Standards

Grade

Pharmaceutical Grade

Is Manufacturer

Samples Provided

Product Description

Naproxen 22204-53-1

AI Product Description

*The following content is generated by AI and is for reference only.

Naproxen is a widely prescribed nonsteroidal anti-inflammatory drug (NSAID) belonging to the propionic acid derivative class. Its chemical identity is defined by the molecular formula C14H14O3 and the CAS Registry Number 22204-53-5. Structurally, it features a naphthalene ring substituted with a methoxy group and a propionic acid moiety, which is critical for its pharmacological activity. As a potent inhibitor of cyclooxygenase enzymes, Naproxen effectively blocks the synthesis of prostaglandins, the endogenous mediators responsible for pain, inflammation, and fever. This mechanism distinguishes it from other analgesics by offering prolonged duration of action, typically allowing for dosing intervals of twelve hours rather than four or six. Clinically, Naproxen serves as a first-line therapy for managing mild to moderate pain, including headaches, dental pain, musculoskeletal disorders, and menstrual cramps. It is particularly effective in treating chronic inflammatory conditions such as osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, and acute gouty arthritis. Beyond its therapeutic applications, Naproxen is available in various formulations, including immediate-release tablets, delayed-release capsules, and oral suspensions, catering to diverse patient needs and compliance requirements. The drug is marketed under numerous brand names globally, most notably Aleve and Naprosyn, reflecting its widespread availability over-the-counter and via prescription. Despite its efficacy, Naproxen carries risks associated with NSAID use, including gastrointestinal ulcers, bleeding, and increased cardiovascular events, necessitating careful patient screening. It is generally contraindicated for individuals with a history of aspirin-sensitive asthma or active peptic ulcer disease. Furthermore, caution is advised during pregnancy, especially in the third trimester, due to potential fetal complications. Long-term monitoring is recommended for patients on high doses to assess renal function and blood pressure. Overall, Naproxen remains a cornerstone in modern pain management protocols, balancing robust anti-inflammatory effects with a favorable safety profile when used appropriately under medical supervision. Its established track record ensures continued relevance in both acute and chronic care settings worldwide.