N-hydroxysuccinimide is a white crystal, which is sensitive to moisture, soluble in water, soluble in acetone, alcohol and ethyl acetate; Slightly soluble in chlorinated hydrocarbons, ethers, toluene and benzene. The product is easy to agglomerate, and the melting point is 99-100 °C. It is used in the synthesis of amino acid protective agents, semi-synthetic kanamycin and pharmaceutical intermediates.
AI Product Description
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<h3>Overview</h3>
<p>N-Hydroxysuccinimide (NHS) is a critical heterocyclic compound used primarily as an activating agent in peptide synthesis and bioconjugation. Produced via oxidation of succinic anhydride, its molecular formula is <strong>C4H5NO3</strong> with CAS number <strong>126-30-7</strong>.</p>
<h3>Application</h3>
<ul>
<li><strong>Pharmaceuticals:</strong> Synthesis of amide bonds for drug manufacturing.</li>
<li><strong>Diagnostics:</strong> Labeling antibodies and enzymes for immunoassays.</li>
<li><strong>Research:</strong> Preparation of NHS esters for protein modification.</li>
</ul>
<h3>Precautions</h3>
<p>Store in a cool, dry place away from moisture to prevent hydrolysis. Handle with appropriate PPE to avoid skin irritation; not intended for direct human clinical use without formulation.</p>