Product Description
N-Arachidonoyl serotonin
Type : griffonia seed extract
Appearance :powder
Part : seed
Extraction Method : Solvent Extraction
Packing : bottle , drum , vacuum packed
Grade :medicine grade
Molecular formula : N30H42N2O2
Function :
1. Inhibitors of fatty acid amide hydrolase (FAAH).
2. It has analgesic effect on rodents.
Contact :
Trading manger : Helen Tan
Whatsapp ： +86 13930229229
Website : www.blrhbio.com
AI Product Description
*The following content is generated by AI and is for reference only.
N-Arachidonoyl serotonin, commonly known as AA-5-HT and identified by CAS Registry Number 187947-37-1, is a sophisticated bioactive lipid mediator belonging to the class of N-acylethanolamines. Structurally, this compound features a serotonin molecule acylated at the nitrogen atom with an arachidonic acid chain, resulting in the molecular formula C26H35NO2. This unique chemical architecture allows AA-5-HT to function as a potent endogenous ligand for specific cannabinoid receptors, particularly the CB1 receptor, although it exhibits distinct pharmacological profiles compared to classical cannabinoids like THC or endocannabinoids such as anandamide.
The primary significance of N-Arachidonoyl serotonin lies in its role within the complex network of lipid signaling pathways that regulate physiological homeostasis. Research indicates that AA-5-HT acts as a modulator of pain perception, inflammation, and vascular tone. Unlike many other fatty acid amides, it possesses a high affinity for certain serotonin receptors alongside cannabinoid receptors, suggesting a dual mechanism of action that bridges serotonergic and endocannabinoid systems. This duality makes it a subject of intense interest in neuroscience and pharmacology, particularly regarding the development of novel therapeutics for chronic pain management, neuroprotection, and the treatment of inflammatory disorders.
In laboratory settings, AA-5-HT serves as a critical reference standard for validating assays designed to detect lipid mediators and for studying receptor binding kinetics. Its synthesis typically involves the enzymatic or chemical coupling of arachidonic acid derivatives with serotonin under controlled conditions. While not currently approved as a commercial drug, its biological activity provides invaluable insights into the pathophysiology of various diseases. Scientists utilize this compound to explore the "entourage effect," where multiple lipid mediators work synergistically. Furthermore, understanding the metabolism and degradation pathways of AA-5-HT helps elucidate how the body regulates immune responses and neuronal excitability. As research progresses, the potential for targeting AA-5-HT specific pathways may lead to breakthrough treatments with fewer side effects than current analgesics or anti-inflammatory agents, highlighting its enduring importance in biomedical science.
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