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N-(1-Oxohexadecyl)-L-glutaMic Acid tert-Butyl Ester

Category:

Other Intermediates

CAS NO:

536721-25-2

Standard:

In-house Standards,

Price Range:

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Main Sales Markets:

North America,Central/South America,Western Europe,Eastern Europe,Australasia,Asia,Middle East,Africa

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Jinan Xinnuo Pharmaceutical Co., Ltd

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Basic Info

CAS Number

536721-25-2

Pharmacopoeia

In-house Standards

Grade

Pharmaceutical Grade

Is Manufacturer

YES

Samples Provided

Product Description

Cigna Qingdao is mainly engaged in the intermediates of febuxostatin, ceflothrin, eprazole, flubiprofen, phenalidone, tovaptan, rivaroxaban and Avanafil, terbinafine intermediates, thioacetamide and thiophene and their derivatives.

AI Product Description

*The following content is generated by AI and is for reference only.

N-(1-Oxohexadecyl)-L-glutamic acid tert-butyl ester is a specialized chemical intermediate primarily utilized in the field of organic synthesis and medicinal chemistry. This compound features a long-chain fatty acyl group attached to the nitrogen atom of an L-glutamic acid backbone, which is protected by a tert-butyl ester moiety. The presence of the hexadecyl chain imparts significant lipophilicity, making this molecule particularly valuable for studies involving membrane permeability, lipid bilayer interactions, and the development of prodrugs designed to enhance bioavailability. The molecular formula for this substance is typically C23H43NO5, reflecting its complex structure comprising twenty-three carbon atoms, forty-three hydrogen atoms, five oxygen atoms, and one nitrogen atom. While specific CAS registry numbers can vary depending on exact stereochemical configurations or salt forms, this particular derivative is often cataloged under unique identifiers used by major chemical suppliers for research-grade materials. Its primary application lies in the preparation of peptidomimetics and bioactive peptides where controlled hydrolysis is required. The tert-butyl ester group serves as a robust protecting group that remains stable under various reaction conditions but can be selectively removed using acidic reagents like trifluoroacetic acid (TFA) to reveal the free carboxylic acid functionality. Researchers frequently employ this compound in the synthesis of novel pharmaceutical agents targeting metabolic disorders, neurological conditions, or cancer. The long alkyl chain may facilitate interaction with specific protein binding sites or aid in self-assembly processes for nanocarrier systems. Furthermore, it acts as a critical building block for creating glutamate-based polymers with tailored degradation rates. Due to its specific structural characteristics, it is strictly intended for laboratory research purposes and is not approved for direct human consumption or therapeutic use outside of clinical trial contexts. Handling requires standard safety precautions, including the use of personal protective equipment, as with most organic esters and amides. In summary, N-(1-Oxohexadecyl)-L-glutamic acid tert-butyl ester represents a versatile tool for advancing drug discovery and understanding lipid-peptide conjugate behavior in biological systems.