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25406-64-8
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Basic Info
CAS Number
25406-64-8
Pharmacopoeia
In-house Standards
Grade
Pharmaceutical Grade
Is Manufacturer
No
Product Description
please call me ,to know more
AI Product Description
*The following content is generated by AI and is for reference only.
Morroniside is a bioactive iridoid glycoside primarily isolated from the root bark of *Cornus officinalis* (commonly known as Chinese Cornus or Shan Zhu Yu), a herb extensively utilized in Traditional Chinese Medicine. Chemically, it serves as a major constituent responsible for several therapeutic effects attributed to this plant species. The molecular formula of Morroniside is C17H24O9, reflecting its structure as a glucosylated derivative of morroniside aglycone. Its corresponding CAS registry number is 3860-19-5, which uniquely identifies this specific chemical entity in scientific databases and regulatory frameworks.
Structurally, Morroniside consists of a secoiridoid core linked to a glucose moiety via a glycosidic bond. This structural configuration significantly influences its solubility profile and biological activity compared to its non-glycosylated counterparts. In pharmacological research, Morroniside has garnered substantial attention for its diverse range of potential health benefits. It exhibits potent anti-inflammatory properties by modulating key signaling pathways involved in the immune response, such as inhibiting the production of pro-inflammatory cytokines like TNF-alpha and IL-6. Furthermore, studies suggest significant neuroprotective effects, indicating its potential utility in managing neurodegenerative conditions associated with oxidative stress and neuronal damage.
Beyond neurological applications, Morroniside demonstrates promising hepatoprotective activities, helping to mitigate liver injury induced by toxins or metabolic disorders. Its antioxidant capacity allows it to scavenge free radicals, thereby reducing cellular oxidative stress. Additionally, emerging evidence points toward its role in regulating glucose metabolism and improving insulin sensitivity, making it a subject of interest for diabetes management strategies. Due to these multifaceted biological activities, Morroniside is increasingly explored not only as a standard reference compound in quality control for herbal medicines but also as a lead candidate for developing novel pharmaceutical agents targeting chronic inflammatory diseases, liver disorders, and cognitive decline. While most current data stems from preclinical models, ongoing research aims to validate its efficacy and safety in human clinical trials, potentially establishing it as a valuable natural therapeutic agent in modern integrative medicine practices.
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