Huateng Pharmaceutical, a global supplier of API intermediates, offers Carfilzomib intermediate Morpholin-4-ylacetic acid (CAS No.: 3235-69-6) for your requirements of R&D, evaluation, pilots and commercial along with supportive technical package required for evaluation.
Application: An intermediate of Carfilzomib (C183460) which is a second-generation proteasome inhibitor that is used as a treatment in relapsed and refractory multiple myeloma.
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Morpholin-4-ylacetic acid is a specialized organic compound widely utilized in the pharmaceutical and agrochemical industries as a versatile synthetic intermediate. With the chemical formula C5H9NO3 and a molecular weight of approximately 131.13 g/mol, this substance features a morpholine ring attached to an acetic acid moiety via a methylene bridge. Its primary CAS Registry Number is 2067-70-9, which serves as its unique identifier for regulatory compliance and inventory management across global supply chains. The molecule exhibits moderate solubility in water and polar organic solvents, making it suitable for various reaction conditions including esterification, amidation, and salt formation processes.
In the realm of medicinal chemistry, Morpholin-4-ylacetic acid acts as a crucial building block for constructing complex heterocyclic structures. It is frequently employed in the synthesis of bioactive compounds possessing anti-inflammatory, antimicrobial, or central nervous system modulating properties. The presence of both the basic nitrogen atom within the morpholine ring and the acidic carboxylic group allows for flexible functionalization, enabling chemists to tailor molecules with specific pharmacokinetic profiles. Furthermore, derivatives of this acid are investigated for their potential applications in developing novel therapeutic agents targeting receptor binding sites.
Beyond pharmaceuticals, this compound finds utility in agricultural research, where it contributes to the development of herbicides and plant growth regulators. Its structural integrity under diverse thermal and chemical conditions ensures stability during multi-step synthesis protocols. Industrial applications also extend to materials science, where it may serve as a precursor for specialized polymers or chelating agents. Safety data indicates that while generally stable, standard laboratory precautions regarding skin and eye irritation should be observed during handling. As a high-purity reagent, Morpholin-4-ylacetic acid is essential for researchers aiming to advance drug discovery pipelines or optimize industrial chemical manufacturing processes. Its availability from major chemical suppliers facilitates rapid prototyping and scale-up operations in modern chemical laboratories worldwide.