Product Description
lower price 98% Almost white crystalline powder Triptorelin 57773-63-4
AI Product Description
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Triptorelin, identified by CAS No. 54889-46-0, is a synthetic decapeptide analogue of gonadotropin-releasing hormone (GnRH). Its molecular formula is C125H173N37O31S2, corresponding to a molar mass of approximately 2,757.0 g/mol. The product typically appears as an almost white crystalline powder with high purity levels, often exceeding 98%, making it suitable for pharmaceutical applications where consistency and quality are paramount. This compound acts as a potent GnRH agonist, initially stimulating the release of luteinizing hormone (LH) and follicle-stimulating hormone (FSH) from the pituitary gland before causing downregulation and desensitization of GnRH receptors due to continuous administration.
Clinically, Triptorelin is widely utilized in the management of hormone-dependent conditions. It serves as a first-line treatment for advanced prostate cancer in men, effectively reducing testosterone levels to castrate concentrations, thereby inhibiting tumor growth. In women, it is employed to treat endometriosis, uterine fibroids, and central precocious puberty by suppressing ovarian function and estrogen production. Additionally, it plays a crucial role in assisted reproductive technologies (ART), such as in vitro fertilization (IVF), where it prevents premature ovulation during controlled ovarian stimulation cycles.
The availability of Triptorelin at competitive prices has expanded its accessibility for global healthcare systems and research institutions. As a long-acting depot formulation, it offers convenience through monthly or quarterly injections, improving patient compliance compared to daily dosing regimens. While generally well-tolerated, side effects may include hot flashes, headache, and injection site reactions, reflecting its profound impact on the hypothalamic-pituitary-gonadal axis. Ongoing research continues to explore novel delivery systems and combination therapies to enhance efficacy and minimize adverse events. With its established safety profile and versatile therapeutic applications, Triptorelin remains a cornerstone medication in modern endocrinology and oncology, providing critical support for patients facing complex hormonal disorders worldwide.