lower price 916~964ug/mg Off-white to pale yellow crystalline powder Cefotaxime sodium 64485-93-4
AI Product Description
*The following content is generated by AI and is for reference only.
Cefotaxime Sodium is a third-generation cephalosporin antibiotic widely recognized for its potent broad-spectrum activity against both Gram-positive and Gram-negative bacteria. Chemically, it is the sodium salt of cefotaxime, characterized by the molecular formula C₁₆H₁₅N₈O₇S₂Na and bearing the CAS Registry Number 63892-05-1. The substance typically appears as an off-white to pale yellow crystalline powder, consistent with high-purity pharmaceutical standards. Its stability and solubility profile make it highly suitable for intravenous and intramuscular administration in clinical settings.
The primary mechanism of action involves the inhibition of bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs), thereby preventing peptidoglycan cross-linking and leading to cell lysis. This unique pharmacological property grants Cefotaxime Sodium exceptional efficacy against beta-lactamase-producing strains that often resist earlier generations of antibiotics. Consequently, it is extensively utilized in the treatment of severe infections including meningitis, septicemia, pneumonia, urinary tract infections, skin and soft tissue infections, and gynecological disorders. Its ability to cross the blood-brain barrier effectively makes it a drug of choice for treating bacterial meningitis caused by susceptible organisms such as *Neisseria meningitidis* and *Haemophilus influenzae*.
In the global pharmaceutical market, Cefotaxime Sodium is supplied by various manufacturers adhering to Good Manufacturing Practices (GMP). Products are often marketed under competitive pricing structures to ensure accessibility for hospitals and clinics worldwide. The raw material specifications generally require a purity level exceeding 95%, ensuring safety and therapeutic consistency. As resistance patterns evolve, this antibiotic remains a cornerstone in empirical therapy protocols due to its reliable spectrum of coverage and favorable safety profile. While side effects can occur, including gastrointestinal disturbances or hypersensitivity reactions, they are generally manageable. The ongoing demand for high-quality Cefotaxime Sodium underscores its critical role in modern antimicrobial stewardship and infection control strategies globally.