Product Description
Lomefloxacin hydrochloride supplier Pharmaceutical API Antibiotics made in china 98079-52-8
AI Product Description
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Lomefloxacin hydrochloride is a third-generation fluoroquinolone antibiotic synthesized and manufactured primarily in China, serving as a critical active pharmaceutical ingredient (API) for systemic antimicrobial therapy. Its molecular formula is C17H18FN3O3·HCl, with the corresponding CAS number 90542-68-6. This compound represents the hydrochloride salt form of lomefloxacin, designed to enhance water solubility and bioavailability for oral administration. As a broad-spectrum antibacterial agent, it functions by inhibiting bacterial DNA gyrase and topoisomerase IV, essential enzymes required for DNA replication, transcription, and repair. Consequently, it effectively halts bacterial growth and leads to cell death.
The primary therapeutic applications of Lomefloxacin hydrochloride include the treatment of various bacterial infections affecting the respiratory tract, skin, soft tissues, urinary tract, and gastrointestinal system. It demonstrates potent activity against both Gram-positive and Gram-negative pathogens, including strains of *Escherichia coli*, *Klebsiella pneumoniae*, *Pseudomonas aeruginosa*, and *Staphylococcus aureus*. Due to its high lipophilicity compared to earlier generations, it achieves superior tissue penetration, making it particularly effective for intracellular infections. The product is widely supplied by Chinese pharmaceutical manufacturers who adhere to international Good Manufacturing Practices (GMP), ensuring high purity and consistency for global markets. These suppliers provide the API in bulk quantities suitable for tablet, capsule, and injectable formulations used in hospitals and clinics worldwide. While generally well-tolerated, clinical usage requires monitoring for potential side effects such as photosensitivity, tendonitis, and central nervous system disturbances. The availability of this cost-effective, high-quality antibiotic from Chinese sources supports global healthcare systems in managing resistant bacterial infections efficiently.