white or almost white crystalline powder,soluble in water,practically inslouble in anhydrous ethanol and in heptane
AI Product Description
*The following content is generated by AI and is for reference only.
<h3>Overview</h3>
<p>Lisinopril is a potent <strong>ACE inhibitor</strong> synthesized via enzymatic hydrolysis of enalaprilat. Its molecular formula is <strong>C₂₁H₃₀N₂O₅</strong> (CAS No. 83915-01-5), primarily manufactured through fermentation and chemical modification processes.</p>
<h3>Application</h3>
<ul>
<li><strong>Hypertension Management:</strong> First-line therapy for lowering blood pressure in chronic care.</li>
<li><strong>Heart Failure:</strong> Adjunct treatment to reduce mortality and hospitalization rates.</li>
<li><strong>Nephroprotection:</strong> Slows progression of diabetic nephropathy in high-risk patients.</li>
</ul>
<h3>Precautions</h3>
<p>Contraindicated in pregnancy due to fetal toxicity; avoid use with potassium-sparing diuretics. Store in <strong>hermetically sealed containers</strong> below 25°C, protected from moisture and light to maintain stability.</p>