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Basic Info
CAS Number
7004-03-7
Pharmacopoeia
In-house Standards
Grade
Food Grade
Is Manufacturer
YES
Samples Provided
YES
Product Description
About The Detailed Introduction Of L-Valine?
The chemical name of L-Valine Powder is 2-amino-3-methylbutyric acid, which is a branched-chain amino acid. It is an essential amino acid and glycogenic amino acid for the human body. It can promote the normal growth of the body, repair tissues, regulate blood sugar, and provide energy required. Isobutyraldehyde can be used as raw material for synthesis. It is white crystal or crystalline powder, soluble in water and almost insoluble in ethanol.
Valine is one of the 20 amino acids that make up proteins. Its chemical name is 2-amino-3-methylbutyric acid. It is a branched-chain amino acid and is also an essential amino acid and glycogenic amino acid for the human body. Valine is an essential amino acid, which means the body cannot produce it on its own and must obtain it through dietary sources. Its natural food sources include grains, dairy products, shiitake mushrooms, peanuts, soy protein and meat. In addition, D-valine also exists in some actinomycins (such as valinomycin). Although most people can get adequate amounts from their diet, cases of valine Chemicalbook acid deficiency are not uncommon. When valine is insufficient, the function of the central nervous system of rats will be disordered, resulting in ataxia and tremors in the limbs. By dissecting and sectioning brain tissue, it was found that there is degeneration of red blood cells. Patients with advanced liver cirrhosis are prone to develop hyperinsulinemia due to liver function damage, resulting in a decrease in branched-chain amino acids in the blood. The ratio of branched-chain amino acids to aromatic amino acids is lower than that of normal people. 3.0~3.5 dropped to 1.0~1.5, so injections of branched-chain amino acids such as valine are commonly used to treat liver failure and damage to these organs caused by alcoholism and drug abuse.
Product Details List
| CAS | 7004-03-7 |
| Molecular weight | 117.146 |
| Chemical formula | C5H11NO2 |
| Density | 1.32 g/cm³ |
| Melting point | 315°C(decomp) |
| Water solubility | 16.5g/100mL |
What Are The Benefits?
L-Valine Powder is one of the 20 amino acids that make up protein. It is an essential 8 amino acid and a glycogenic amino acid for the human body. It works together with the other two high-concentration amino acids (isoleucine and leucine) to promote normal growth of the body. Repair tissue, regulate blood sugar, and provide needed energy. When participating in strenuous physical activity, valine can provide extra energy to the muscles to produce glucose to prevent muscle weakness. It also helps remove excess nitrogen (potential toxins) from the liver and transports needed nitrogen throughout the body.
Valine is an essential amino acid, which means the body cannot produce it on its own and must obtain it through dietary sources. Its natural food sources include grains, dairy products, shiitake mushrooms, peanuts, soy protein and meat. In addition, D-valine is also present in some actinomycins (such as valinomycin). Although most people can get adequate amounts from their diet, cases of valine deficiency are common. When valine is insufficient, the function of the central nervous system of the brain will be disordered, resulting in ataxia and tremors in the limbs. By dissecting and sectioning brain tissue, it was found that there is degeneration of red blood cells. Patients with advanced liver cirrhosis are prone to develop hyperinsulinemia due to liver function damage, resulting in a decrease in branched-chain amino acids in the blood. The ratio of branched-chain amino acids to aromatic amino acids is lower than that of normal people. 3.0~3.5 dropped to 1.0~1.5, so injections of branched-chain amino acids such as valine are commonly used to treat liver failure and damage to these organs caused by alcoholism and drug abuse. In addition, it also acts as a therapeutic agent to speed up wound healing.
Valine is a branched-chain amino acid that works with two other high-concentration amino acids (isoleucine and leucine) to promote normal body growth, repair tissue, regulate blood sugar, and provide needed energy. In addition, valine's effects include stimulating the central nervous system, which is required for proper mental functioning. When participating in strenuous physical activity, valine can provide extra energy to the muscles to produce glucose to prevent muscle weakness. It also helps remove excess nitrogen (potential toxins) from the liver and transports needed nitrogen throughout the body. Valine may also help treat liver and gallbladder disease.
1. Provide Energy
Studies have shown that the uptake of valine in the myocardium and skeletal muscles of rats significantly increases during exercise. Supplementing branched-chain amino acids can promote gluconeogenesis, increase glycogen in the muscles, and relieve the pressure on the myocardium caused by exercise, indicating that valine Acid and other branched-chain amino acids are good energy sources that replace glycogen during exercise in rats.
2. Influence Amino Acid Metabolism
Alanine aminotransferase (ALT) and aspartate aminotransferase (AST) are widely distributed in various tissues and organs of the body. These two enzymes play an important role in amino acid metabolism and are the two most important aminotransferases in the body. Experimental studies have shown that valine levels can significantly affect ALT in serum, hepatopancreas and muscle and AST activity in serum and hepatopancreas.
3. Promote Lactation Performance
Adding valine can increase the concentration of prolactin, which can stimulate the development of mammary gland alveoli and promote the production and secretion of milk, initiating and maintaining lactation. In addition, valine can also promote the anabolism of growth hormone, which is the core of regulating animal growth and development. It can increase animal growth rate, promote muscle growth, reduce fat content, and is also an important hormone in regulating mammary gland development. one.
4. Improve Immunity
Valine and other branched-chain amino acid supplements improve the ability to convert into glutamine, which is known to be an important energy substance for lymphocytes and neutrophils and can increase the proliferation of white blood cells and lymphocytes. Studies have shown that lack of BCAA during exercise leads to atrophy of the thymus and spleen and damage to lymphoid tissue. In particular, valine deficiency can significantly hinder the growth of the thymus and peripheral lymphoid tissue, and inhibit the proliferation of neutral and acidic leukocytes. In addition, valine also affects the form or activity of immunoglobulins, which play an important role in preventing bacterial and viral invasion, activating complement, neutralizing toxins, and killing tumor cells.
5. Antioxidant Effect
Superoxide dismutase SOD is an important biological enzyme for organisms to defend against oxidative damage. It can scavenge excessive oxygen free radicals in the body and is a natural barrier for organisms to resist external stress. Studies have shown that adding feed valine content can significantly Increase SOD activity in serum.
6. Anti-Fatigue Effect
Valine can provide necessary glucose to various muscles in our body, and can also reduce the synthesis of 5-hydroxytryptamine through competitive inhibition to delay the onset of fatigue and prevent soreness and weakness, thereby protecting muscles.
7. Maintain Normal Function Of The Nervous System
Amino acids, while acting as neurotransmitters, are also precursors of many other neurotransmitters and are widely used clinically to reduce central nervous system disorders caused by liver damage in the elderly. Clinical investigations have shown that instilling branched-chain amino acids can also increase ventilation, improve sleep patterns in patients with sleep disorders, increase appetite and regulate mood. Finally, valine also has an inhibitory effect on neurological diseases, such as nervous system degeneration. It mainly affects the nerves of the human body by affecting the myelin sheath covering the nerves.
8. Promote Trauma Recovery
Since the body's amino acid concentration and amino acid profile undergo a series of changes in trauma patients after stress, whether the type of amino acids supported by metabolism is suitable for the body's needs will directly affect the body's amino acid metabolism. Meta-analysis results show that early administration of branched-chain amino acids to trauma patients can better improve the patient's nitrogen balance, increase total protein and albumin levels, and reduce postoperative complications [4].
9. Protect Myocardium
In the process of heart failure, the gene expression of valine and other branched-chain amino acid metabolic enzymes is inhibited, leading to defects in branched-chain amino acid metabolism and accumulation of branched-chain keto acids as metabolic intermediates. Defects in branched-chain amino acid metabolism damage the contractile function of the heart and promote the development of heart failure.
10. Regulate Liver Metabolism
Patients with chronic liver disease often suffer from multiple metabolic disorders. A decrease in the ratio of serum branched-chain amino acids (BCAA) to aromatic amino acids (AAA) is a sign of cirrhosis. Clinical studies have shown that intravenous administration of branched-chain amino acids can improve hepatic encephalopathy with hyperammonemia caused by cirrhosis. The consensus of the American Society for Parenteral and Enteral Nutrition and the European Society of Clinical Nutrition and Metabolism is that branched-chain amino acid supplementation is currently only recommended for cirrhotic patients with chronic hepatic encephalopathy who are unresponsive to drug treatment.
11.Other Functions
Improve calcium absorption, promote bone growth; promote brain development, promote fat metabolism, regulate the pineal gland, mammary gland, corpus luteum and ovary, prevent cell degeneration; reduce or prevent the occurrence of herpes simplex infection; help eliminate some unhealthy Pregnancy symptoms; if valine is deficient, it will reduce people's sensitivity, women will stop menstruating, and experience symptoms such as anemia, dizziness, dizziness, and nausea.
What Are The Application Directions?
L-Valine Powder is one of the three major branched-chain amino acids. It is a glycogenic amino acid and is mainly metabolized through the glucose pathway after oxidative dehydrogenation. It works together with leucine (ketogenic amino acid) and isoleucine (glycogenic and ketogenic amino acid), and is interconnected with the tricarboxylic acid cycle to achieve the conversion of the three major nutrients (protein, sugar, fat) in the body. It has physiological functions such as oxidative energy supply, promoting protein synthesis, inhibiting protein degradation, promoting gluconeogenesis, etc., and plays an important role in biological applications.
1. Amino Acid Drugs
Amino acid drugs. L-Valine is one of the three branched-chain amino acids and is an essential amino acid. It can be used together with other essential amino acids to prepare amino acid infusions and comprehensive amino acid preparations. It can treat liver failure and central nervous system dysfunction.
2. Feed Additives
① Adding L-valine to the diet of lactating livestock can increase milk production. At higher lysine levels, valine becomes the first limiting amino acid.
②Improve the immune function of animals. Valine can promote the transformation of animal bone cells into mature T cells. When animals lack valine, their ability to synthesize specific antibodies is reduced, and the antibody response to the virus is reduced.
③Influence animal endocrine levels. Studies have shown that adding valine to the diets of lactating sows and lactating rats increases plasma concentrations of prolactin and growth hormone.
3. Nutritional Supplements
It can be used as a food additive. Valine (1g/kg) is added to rice cakes. The product has a sesame aroma and can also be used to improve the flavor of bread.
Company Introduction And Certificates Obtained
Shaanxi Yuantai Biological Technology Co., Ltd (YTBIO) was established in 2014, mainly supplying herbal extracts, functional cosmetic raw materials, organic products, etc. We have our own factories, R&D and quality inspection teams, and have the conditions for development, production, and quality assurance. At present, we have obtained ISO9001, ISO22000, HALAL, KOSHER, HACCP, FDA, and other certificates. Therefore, the quality of our products is guaranteed, and it is our original intention to bring high-quality products to customers.
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