Category:
Vitamin
CAS NO:
151533-22-1
Standard:
ChP,USP,BP,EP,JP,In-house Standards,IP,Ph. Int,
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L-5 Methyltetrahydrofolate Calcium
Price Range:
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Main Sales Markets:
North America,Central/South America,Western Europe,Eastern Europe,Australasia,Asia,Middle East,Africa
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Quanzhou Fortune Biopharma Co.,Ltd.
4
Years
Basic Info
CAS Number
151533-22-1
Pharmacopoeia
ChP,USP,BP,EP,JP,In-house Standards,IP,Ph. Int
Grade
Pharmaceutical Grade
Is Manufacturer
YES
Samples Provided
NO
Product Description
L-5-Methyltetrahydrofolate Calcium is the active form of folic acid and plays a crucial role in one-carbon metabolism and methylation reactions. It has broad application value in nutritional supplements, clinical treatments, and food fortification, especially for people with folic acid metabolism disorders.
AI Product Description
*The following content is generated by AI and is for reference only.
L-5-Methyltetrahydrofolate Calcium, commonly known as L-5-MTHF Calcium or 5-MTHF-Ca, is the biologically active form of folate (Vitamin B9) widely utilized in nutritional supplements and pharmaceutical formulations. Its chemical formula is C20H26CaN8O14, and it carries the CAS registry number 19763-63-0. Unlike synthetic folic acid, which requires enzymatic conversion by the MTHFR enzyme to become bioavailable, L-5-MTHF Calcium is already in its reduced, methylated state. This unique structural characteristic allows for immediate absorption and utilization by the body without metabolic bottlenecks, making it particularly beneficial for individuals with genetic polymorphisms such as the MTHFR mutation that impair folic acid processing.
The primary application of this compound lies in supporting cardiovascular health and neurological function. It plays a critical role in the methylation cycle, facilitating the conversion of homocysteine into methionine. Elevated homocysteine levels are a significant risk factor for heart disease and stroke; thus, adequate intake of L-5-MTHF Calcium helps maintain optimal homocysteine concentrations. Furthermore, it is essential for DNA synthesis and repair, cell division, and fetal development during pregnancy. Many prenatal vitamins now feature L-5-MTHF Calcium instead of folic acid to ensure maximum bioavailability for expectant mothers, reducing the risk of neural tube defects while accommodating those with specific genetic needs.
In the dietary supplement industry, this calcium salt offers superior stability compared to other forms of 5-MTHF. The calcium counterion enhances solubility and shelf life, ensuring the ingredient remains potent throughout storage and digestion. It is frequently marketed as a high-potency vitamin B complex component for energy metabolism and mood regulation, given its involvement in neurotransmitter synthesis. Due to its natural origin and direct bioactivity, L-5-MTHF Calcium has become the gold standard for advanced nutritional support, bridging the gap between dietary intake and cellular requirement efficiently.
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