Huateng Pharmaceutical, a global supplier of pharmaceutical intermediates & chemical products & biological reagent & PEG derivatives, offers , CAS NO.108321-18-2 for your requirements of R&D, evaluation, pilots and commercial along with supportive technical package required for evaluation.
Application: It is one of the excipients of COVID-19 Vaccines.
*The following content is generated by AI and is for reference only.
L-α-Distearoyl phosphatidic acid sodium salt is a specialized synthetic phospholipid derivative widely utilized in pharmaceutical and cosmetic industries for its unique physicochemical properties. With the Chemical Abstracts Service (CAS) registry number 67204-83-5, this compound serves as a critical building block in advanced drug delivery systems and emulsion formulations. Its molecular formula is typically represented as C₃₆H₇₀NaO₈P, reflecting a structure composed of two stearic acid chains esterified to the glycerol backbone of phosphatidic acid, neutralized with a sodium ion. This specific configuration imparts excellent stability and biocompatibility, making it ideal for encapsulating hydrophobic therapeutic agents.
In the realm of cosmetics, L-α-Distearoyl phosphatidic acid sodium salt functions as a potent emulsifier and skin conditioning agent. It helps stabilize oil-in-water emulsions, ensuring uniform texture and prolonged shelf life for creams, lotions, and serums. Furthermore, its ability to interact with cell membranes suggests potential applications in transdermal drug delivery, where it can facilitate the penetration of active ingredients into deeper skin layers without causing significant irritation. The sodium salt form enhances water solubility compared to its free acid counterpart, broadening its utility in aqueous-based formulations.
Research indicates that this phospholipid may also play a role in modulating immune responses and promoting tissue repair, although these applications are still under investigation. Its amphiphilic nature allows it to form liposomes and micelles, which are essential for targeting specific tissues in oncology treatments or gene therapy vectors. As the demand for sophisticated nanomedicine solutions grows, derivatives like this continue to attract attention from formulation scientists seeking safer, more effective delivery vehicles. Overall, L-α-Distearoyl phosphatidic acid sodium salt represents a versatile tool bridging the gap between fundamental lipid chemistry and high-performance industrial applications, offering manufacturers a reliable component for developing next-generation personal care and medical products.