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Ketorolac Tromethamine USP36

Category:

Intermediates&Fine Chemicals

CAS NO:

74103-07-4

Standard:

In-house Standards,

Price Range:

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Main Sales Markets:

North America,Central/South America,Western Europe,Eastern Europe,Australasia,Asia,Middle East,Africa

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INNER MONGOLIA YUANHONG FINE CHEMICAL CO., LTD.

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Basic Info

CAS Number

74103-07-4

Pharmacopoeia

In-house Standards

Grade

Pharmaceutical Grade

Is Manufacturer

Samples Provided

Product Description

Ketorolac Tromethamine USP36 74103-07-4

AI Product Description

*The following content is generated by AI and is for reference only.

Ketorolac Tromethamine, adhering to the United States Pharmacopeia (USP) 36 monograph standards, is a potent non-steroidal anti-inflammatory drug (NSAID) widely utilized for the short-term management of moderate to severe acute pain. Chemically, it is represented by the molecular formula C15H20N2O4 and carries the CAS Registry Number 74103-86-9. As the tromethamine salt form of ketorolac, this compound offers enhanced water solubility compared to its acid counterpart, making it particularly suitable for parenteral administration via intramuscular or intravenous routes. The primary therapeutic application of Ketorolac Tromethamine lies in its ability to inhibit cyclooxygenase enzymes, thereby blocking the synthesis of prostaglandins responsible for inflammation, fever, and pain signaling. It is frequently prescribed as an alternative to opioids in postoperative settings, emergency departments, and trauma care, providing effective analgesia without the risk of respiratory depression associated with narcotic agents. Due to its high potency, it is strictly indicated for short-term use, typically not exceeding five days, to minimize the risk of serious gastrointestinal bleeding, renal impairment, and cardiovascular events common with prolonged NSAID therapy. Beyond clinical settings, this pharmaceutical agent plays a critical role in multimodal pain management protocols, often used in combination with other analgesics to reduce overall opioid consumption. Its rapid onset of action makes it ideal for managing conditions such as renal colic, migraine headaches, and acute musculoskeletal injuries. Strict adherence to dosage guidelines is essential, as the drug possesses a narrow therapeutic index. While highly effective for acute pain relief, contraindications include active peptic ulcer disease, recent coronary artery bypass graft surgery, and severe renal failure. Overall, Ketorolac Tromethamine USP36 remains a cornerstone medication in modern pain management strategies, balancing efficacy with safety when used appropriately under medical supervision.