Irinotecan HCl Trihydrate other active pharmaceutical ingredients,,Active Pharmaceutical Ingredients,Other Active Pharmaceutical Ingredients
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Product Description
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AI Product Description
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<h3>Overview</h3>
<p>Irinotecan HCl Trihydrate is a water-soluble prodrug of camptothecin used in oncology. Synthesized via enzymatic or chemical hydrolysis, its molecular formula is C<sub>25</sub>H<sub>38</sub>N<sub>4</sub>O<sub>6</sub>·HCl·3H<sub>2</sub>O (CAS: 170907-07-6).</p>
<h3>Application</h3>
<ul>
<li>Chemotherapy formulations for metastatic colorectal cancer.</li>
<li>Combination therapy with fluoropyrimidines and leucovorin.</li>
<li>Investigational use in solid tumor clinical trials.</li>
</ul>
<h3>Precautions</h3>
<p>Requires strict dose adjustment for patients with hepatic impairment. Store below 25°C in dry conditions to prevent hydrolysis. Handle as cytotoxic agent using PPE to avoid dermal exposure.</p>