Product Description
Hydrocortisone acetateEP/ USP API Hormone made in china 50-03-3
AI Product Description
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Hydrocortisone acetate is a widely utilized corticosteroid active pharmaceutical ingredient (API) derived from hydrocortisone through acetylation. Primarily manufactured in China by leading pharmaceutical firms adhering to rigorous international standards such as the European Pharmacopoeia (EP) and United States Pharmacopeia (USP), this compound serves as a critical therapeutic agent in dermatology, ophthalmology, and rheumatology. Its molecular formula is C23H32O6, with a molecular weight of approximately 404.5 g/mol. The substance is uniquely identified by the CAS number 51-06-7.
As a prodrug of hydrocortisone, Hydrocortisone acetate exhibits enhanced lipophilicity compared to its parent compound, allowing for superior penetration into skin layers and ocular tissues when formulated into topical creams, ointments, or eye drops. Once absorbed, it is rapidly converted into active hydrocortisone within the body, exerting potent anti-inflammatory, antipruritic, and immunosuppressive effects. This mechanism makes it highly effective in treating various inflammatory skin conditions, including eczema, psoriasis, allergic dermatitis, and insect bites. In ophthalmic applications, it helps reduce inflammation associated with allergic conjunctivitis and post-surgical recovery. Furthermore, it is sometimes used in combination therapies for rheumatic disorders to manage joint swelling and pain.
The production of Hydrocortisone acetate in China has gained global recognition due to advanced fermentation technologies and semi-synthetic processes that ensure high purity and potency. Manufacturers strictly follow Good Manufacturing Practices (GMP) to guarantee batch-to-batch consistency and safety profiles required for export to North America and Europe. While generally safe for short-term use, long-term application requires medical supervision to avoid potential side effects like skin thinning or systemic absorption issues. As a versatile hormone-based API, Hydrocortisone acetate remains a cornerstone in modern pharmacotherapy, bridging the gap between effective symptom management and patient comfort across diverse clinical settings worldwide. Its availability in bulk form supports the formulation of numerous generic and branded medications globally.