white or almost white granular solid,odorless tasteless
*The following content is generated by AI and is for reference only.
<h3>Overview</h3>
<p><strong>HPMCP</strong> (Hydroxypropyl Methylcellulose Phthalate) is a synthetic polymer widely used as an enteric coating agent in pharmaceutical manufacturing. Synthesized via esterification of hydroxypropyl methylcellulose with phthalic anhydride, it features the molecular formula <strong>C<sub>12</sub>H<sub>14</sub>O<sub>5</sub>(C<sub>6</sub>H<sub>4</sub>(COO)<sub>n</sub>)<sub>m</sub></strong> and CAS number <strong>9004-88-8</strong>.</p>
<h3>Application</h3>
<ul>
<li>Oral solid dosage forms to protect acid-labile drugs from gastric degradation.</li>
<li>Coating for tablets and pellets ensuring release specifically in the intestinal tract (pH > 5.5).</li>
<li>Encapsulation of probiotics and enzymes requiring protection against stomach acidity.</li>
</ul>
<h3>Precautions</h3>
<p>Storage requires dry conditions below 25°C to prevent hydrolysis. Handling necessitates dust masks to avoid respiratory irritation. Not recommended for patients with known hypersensitivity to cellulose derivatives or phthalates.</p>