Category:
Plant Extracts
CAS NO:
35354-74-6
Standard:
ChP,USP,BP,EP,In-house Standards,
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Basic Info
CAS Number
35354-74-6
Pharmacopoeia
ChP,USP,BP,EP,In-house Standards
Grade
Food Grade
Is Manufacturer
YES
Packaging & Delivery
Packaging Specification
1kg/bag 25kg/drum
Minimum Order Quantity
25KG
Delivery Cycle
3 working days
Product Description
We are professional Raw Material Manufacturer, with more than 10 years' experience.
Please contact us for more information and detailed quotation
Email: sales12@sgonekbio.com
Phone/WhatsApp/Wechat: +86 13572550462
AI Product Description
*The following content is generated by AI and is for reference only.
Honokiol is a potent bioactive lignan isolated primarily from the bark of Magnolia species, such as *Magnolia officinalis* and *Magnolia grandiflora*. With the molecular formula C₁₈H₁₈O₂ and a CAS registry number of 27150-68-3, this compound has garnered significant attention in pharmacological research for its diverse therapeutic potential. Structurally characterized by two phenol rings connected by an ether bridge, honokiol exhibits excellent lipophilicity, allowing it to readily cross the blood-brain barrier, which is crucial for its neurological applications.
The primary utility of honokiol lies in its multifaceted biological activities, including anti-inflammatory, antioxidant, neuroprotective, and anticancer properties. It functions by modulating various signaling pathways, such as NF-κB and STAT3, thereby suppressing chronic inflammation and inhibiting tumor cell proliferation. In the realm of neuroscience, honokiol demonstrates anxiolytic and sedative effects by acting as a positive allosteric modulator of GABA-A receptors, offering a natural alternative to synthetic benzodiazepines without the associated risk of severe dependence. Furthermore, emerging studies suggest its efficacy in mitigating cognitive decline and protecting neurons against ischemic injury.
Beyond clinical research, honokiol is increasingly incorporated into dietary supplements and nutraceuticals aimed at promoting relaxation, improving sleep quality, and supporting overall metabolic health. Its ability to induce apoptosis in cancer cells while sparing normal tissues makes it a promising candidate for adjunctive cancer therapies. Additionally, due to its strong free radical scavenging capabilities, it serves as a valuable ingredient in cosmetic formulations designed to combat oxidative stress and skin aging. While generally recognized as safe with a favorable toxicity profile, ongoing clinical trials continue to explore optimal dosages and specific indications. As research advances, honokiol stands out as a versatile phytochemical bridging traditional herbal medicine and modern evidence-based therapeutics, holding immense promise for future drug development and wellness products globally.
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