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Other Specialized Reagents

homopiperazine

Category:

Other Specialized Reagents

CAS NO:

505-66-8

Standard:

In-house Standards,

Price Range:

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Main Sales Markets:

North America,Central/South America,Western Europe,Eastern Europe,Asia

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Hunan HuaTeng Pharmaceutical Co., Ltd.

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Basic Info

CAS Number

505-66-8

Pharmacopoeia

In-house Standards

Grade

Pharmaceutical Grade

Is Manufacturer

Product Description

Huateng Pharma provides Homopiperazine (CAS No. 505-66-8), an intermediate of Fasudil, with 99% purity and best price. Homopiperazine acts as a corrosion inhibitor for iron. It has also been used in the preparation of potent H3 receptor antagonists for use as treatments for neurodegenerative conditions such as Alzheimer's disease.

AI Product Description

*The following content is generated by AI and is for reference only.

Homopiperazine, chemically known as 1,4-diazepane, is a saturated heterocyclic compound featuring a seven-membered ring structure containing two nitrogen atoms at the 1 and 4 positions. Its molecular formula is C5H12N2, and it carries the CAS Registry Number 3697-80-9. Unlike its six-membered counterpart, piperazine, homopiperazine exhibits distinct conformational flexibility due to the additional methylene group in the ring, which significantly influences its steric properties and reactivity patterns in synthetic chemistry. This versatile organic intermediate serves as a crucial building block in the pharmaceutical and agrochemical industries. In medicinal chemistry, homopiperazine derivatives are frequently investigated for their potential biological activities, including antihypertensive, anti-inflammatory, and central nervous system effects. The unique spatial arrangement of the nitrogen atoms allows for specific interactions with various receptor sites, making it a valuable scaffold for designing novel drug candidates. Researchers often modify the homopiperazine core by attaching different functional groups to enhance potency, selectivity, or metabolic stability. Beyond pharmaceutical applications, homoppperazine is utilized in the synthesis of advanced materials and coordination complexes. Its lone pair electrons on the nitrogen atoms enable it to act as an effective chelating agent for metal ions, forming stable complexes useful in catalysis and material science. Additionally, the compound plays a role in the development of specialized polymers and ligands where controlled geometry is essential. Due to its relative instability compared to piperazine under certain conditions, handling requires careful control of temperature and pH to prevent unwanted polymerization or decomposition. While not as commercially ubiquitous as piperazine, homopiperazine remains a significant entity in research laboratories focusing on heterocyclic chemistry. Its structural nuances provide chemists with a unique platform to explore structure-activity relationships (SAR) and develop next-generation therapeutic agents. As global demand for innovative drugs grows, the importance of such specialized heterocycles continues to rise, driving further investigation into their synthesis and application across diverse scientific fields.