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<h3>Overview</h3>
<p><strong>H-DL-Phe(4-Cl)-OH</strong> (CAS 1098-67-5) is a non-natural amino acid derivative, specifically <strong>4-chloro-DL-phenylalanine</strong>. Synthesized via chlorination of phenylalanine or asymmetric synthesis routes, it serves as a critical building block for peptide drug development. Its molecular formula is C<sub>9</sub>H<sub>10</sub>ClNO<sub>2</sub>.</p>
<h3>Application</h3>
<ul>
<li><strong>Pharmaceuticals:</strong> Intermediate for synthesizing ACE inhibitors and antiviral peptides.</li>
<li><strong>Research:</strong> Used in medicinal chemistry to study structure-activity relationships (SAR).</li>
<li><strong>Bioconjugation:</strong> Modified into fluorescent probes for protein labeling.</li>
</ul>
<h3>Precautions</h3>
<p>Store under inert atmosphere at 2-8°C away from moisture. Avoid inhalation; wear PPE including gloves and goggles. Not approved for direct clinical use without formulation into active pharmaceutical ingredients.</p>