Product Description
Glucagon is produced in the α-cells of the islets of Langerhans. The hormone opposes the action of insulin. Glucagon promotes the synthesis and mobilization of glucose from glycogen in the liver. The generation of glucose from lipids is regulated by gluc
AI Product Description
*The following content is generated by AI and is for reference only.
<h3>Overview</h3>
<p>Glucagon-peptides are bioactive chains primarily synthesized via <strong>recombinant DNA technology</strong>. They regulate glucose metabolism by stimulating hepatic glycogenolysis. The core structure typically corresponds to the human glucagon sequence, with a molecular formula of <strong>C153H225N45O51S3</strong> and CAS number <strong>16941-32-5</strong>.</p>
<h3>Application</h3>
<ul>
<li><strong>Diagnostics:</strong> Used as a reference standard in immunoassays for endocrine research.</li>
<li><strong>Therapeutics:</strong> Administered intravenously to treat severe hypoglycemia when oral intake is impossible.</li>
<li><strong>Gastric Motility:</strong> Employed in radiographic imaging to reduce gastric emptying time during upper GI procedures.</li>
</ul>
<h3>Precautions</h3>
<p>Strictly contraindicated for patients with pheochromocytoma or insulinoma. Store lyophilized powder at <strong>-20°C</strong> in a dry environment; reconstituted solutions must be used immediately to prevent degradation.</p>