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Furosemide BP/USPPharmaceutical Diuretics made in china

Category:

Intermediates&Fine Chemicals

CAS NO:

54-31-9

Standard:

In-house Standards,

Price Range:

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Main Sales Markets:

North America,Central/South America,Western Europe,Eastern Europe,Australasia,Asia,Middle East,Africa

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INNER MONGOLIA YUANHONG FINE CHEMICAL CO., LTD.

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Basic Info

CAS Number

54-31-9

Pharmacopoeia

In-house Standards

Grade

Pharmaceutical Grade

Is Manufacturer

Samples Provided

Product Description

Furosemide BP/USPPharmaceutical Diuretics made in china 54-31-9

AI Product Description

*The following content is generated by AI and is for reference only.

Furosemide, a potent loop diuretic widely recognized under the British Pharmacopoeia (BP) and United States Pharmacopeia (USP) standards, is extensively manufactured in China for global pharmaceutical distribution. Chemically known as 4-chloro-2-(furan-2-ylmethylamino)-5-sulfamoylbenzoic acid, its molecular formula is C12H11ClN2O5S, with the corresponding CAS Registry Number 54-31-9. This white to off-white crystalline powder exhibits low solubility in water but dissolves readily in alkaline solutions, making it highly effective when formulated into tablets, injectables, or oral solutions. The primary therapeutic application of Furosemide lies in the management of edema associated with congestive heart failure, cirrhosis of the liver, and renal disease, including nephrotic syndrome. By inhibiting the reabsorption of sodium and chloride in the thick ascending limb of the loop of Henle in the kidney, it promotes rapid excretion of water and electrolytes, thereby reducing blood volume and lowering blood pressure. Consequently, it is also frequently utilized as an antihypertensive agent, often in combination with other medications. Its rapid onset of action makes it indispensable in emergency settings for acute pulmonary edema. China serves as a major production hub for Furosemide due to advanced chemical synthesis capabilities and strict adherence to international quality control measures required by BP and USP specifications. Manufacturers ensure high purity levels, typically exceeding 98%, to meet rigorous global regulatory demands. While generally well-tolerated, clinical use requires monitoring of electrolyte balance, particularly potassium, magnesium, and calcium, as excessive diuresis can lead to dehydration and hypotension. Despite these considerations, Furosemide remains a cornerstone in cardiovascular and renal pharmacotherapy worldwide, valued for its reliability, efficacy, and cost-effectiveness in treating fluid overload conditions across diverse patient populations.