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Fosfomycin calcium CP/EP ≥98.0% Pharmaceutical API made in china

Category:

Intermediates&Fine Chemicals

CAS NO:

26472-47-9

Standard:

In-house Standards,

Price Range:

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Main Sales Markets:

North America,Central/South America,Western Europe,Eastern Europe,Australasia,Asia,Middle East,Africa

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INNER MONGOLIA YUANHONG FINE CHEMICAL CO., LTD.

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Basic Info

CAS Number

26472-47-9

Pharmacopoeia

In-house Standards

Grade

Pharmaceutical Grade

Is Manufacturer

Samples Provided

Product Description

Fosfomycin calcium CP/EP ≥98.0% Pharmaceutical API made in china 26472-47-9

AI Product Description

*The following content is generated by AI and is for reference only.

Fosfomycin calcium, a stable calcium salt derivative of the broad-spectrum antibiotic fosfomycin tromethamine, serves as a critical active pharmaceutical ingredient (API) in global healthcare. Manufactured in China to meet stringent international standards such as the Chinese Pharmacopoeia (CP) and European Pharmacopoeia (EP), this high-purity compound typically exhibits a potency of 98.0% or higher. Its molecular formula is C₆H₁₂CaO₆P₂, reflecting the complex coordination between the organic fosfomycin moiety and the calcium ion, which enhances stability and solubility compared to its free acid form. The substance is identified by CAS number 13657-24-4 for the calcium salt variant, distinguishing it from other salts like tromethamine. Primarily utilized in the treatment of uncomplicated urinary tract infections (UTIs), including cystitis caused by susceptible strains of Escherichia coli and Klebsiella species, Fosfomycin calcium acts by inhibiting bacterial cell wall synthesis. It specifically targets the enzyme MurA (enolpyruvyl transferase), preventing the formation of peptidoglycan precursors essential for bacterial structural integrity. This unique mechanism of action results in minimal cross-resistance with other antibiotic classes, making it a valuable option for empiric therapy and cases involving multidrug-resistant pathogens. Beyond UTIs, research continues into its potential applications for treating osteomyelitis and surgical prophylaxis when administered intravenously or orally, though oral administration remains the most common route for acute lower urinary tract infections due to rapid absorption and high urinary concentration. As a pharmaceutical API produced in China, this product adheres to rigorous Good Manufacturing Practice (GMP) guidelines, ensuring consistent quality, purity, and safety for downstream formulation into tablets, capsules, or sterile injectables. The calcium salt form offers distinct advantages regarding shelf-life and handling properties, facilitating its integration into various dosage forms required by global markets. With rising antimicrobial resistance worldwide, Fosfomycin calcium remains an indispensable tool in modern pharmacotherapy, supporting clinical efforts to combat infectious diseases effectively while maintaining a favorable safety profile for patients.