*The following content is generated by AI and is for reference only.
<h3>Overview</h3>
<p><strong>Fmoc-Lys(Boc)-Thr{psi(Me,Me)pro}-OH</strong> is a non-natural peptide building block featuring a methylene-bridged proline analog. This compound facilitates rigidified backbone structures in solid-phase synthesis, enhancing proteolytic stability.</p>
<ul>
<li><strong>Molecular Formula:</strong> C28H45N3O9</li>
<li><strong>CAS Number:</strong> 176033-66-2</li>
</ul>
<h3>Application</h3>
<ul>
<li><strong>Peptide Drug Discovery:</strong> Used to construct constrained cyclic peptides for improved receptor binding affinity.</li>
<li><strong>Pharmaceutical R&D:</strong> Serves as a key intermediate for synthesizing therapeutic candidates targeting GPCRs.</li>
<li><strong>Biomaterials Research:</strong> Applied in developing stable peptide hydrogels and scaffolds.</li>
</ul>
<h3>Precautions</h3>
<ul>
<li>Store under inert atmosphere at -20°C to prevent racemization or degradation.</li>
<li>Requires PPE handling due to potential sensitization; avoid inhalation of dust.</li>
<li>Not for direct clinical use; intended solely for research and development purposes.</li>
</ul>