*The following content is generated by AI and is for reference only.
<h3>Overview</h3>
<p>Fmoc-Gly-Cys(Psi(Dmp,H)pro)-OH is a specialized <strong>peptide building block</strong> featuring an Fmoc-protected glycine and a modified cysteine residue with a diketopiperazine-like proline mimic. This compound serves as a critical intermediate in <strong>solid-phase peptide synthesis (SPPS)</strong> for constructing complex therapeutic sequences. The molecular formula is C<sub>24</sub>H<sub>30</sub>N<sub>2</sub>O<sub>8</sub>S, with CAS No. 1697654-68-2.</p>
<h3>Application</h3>
<ul>
<li><strong>Pharmaceutical R&D:</strong> Synthesis of cyclic peptides and conformationally constrained drug candidates.</li>
<li><strong>Bioconjugation:</strong> Preparation of peptide-drug conjugates (PDCs) requiring specific stereochemistry.</li>
<li><strong>Proteomics:</strong> Generation of standard references for mass spectrometry calibration.</li>
</ul>
<h3>Precautions</h3>
<p>Store under inert atmosphere at -20°C to prevent racemization or hydrolysis. Handle with appropriate PPE due to potential sensitization risks; avoid direct contact with skin and eyes. Not approved for clinical use directly; intended solely for laboratory research purposes.</p>