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CAS NO:
259793-88-9
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Basic Info
CAS Number
259793-88-9
Pharmacopoeia
In-house Standards
Grade
Pharmaceutical Grade
Is Manufacturer
No
Samples Provided
YES
Product Description
GMP approved factory，stable supplying, competitive price
AI Product Description
*The following content is generated by AI and is for reference only.
Favipiravir, often referenced in scientific databases under the designation INTS for specific industrial or research batch identifiers, is a broad-spectrum antiviral agent with significant clinical relevance. Its chemical identity is defined by the molecular formula C5H4FN3O2 and carries the CAS registry number 109784-68-7. Structurally, it belongs to the class of pyrazinecarboxamide derivatives, featuring a fluorinated pyrazine ring that is crucial for its biological activity. This unique structure allows the drug to function as a guanosine analog, effectively interfering with viral RNA synthesis.
The primary mechanism of action involves the inhibition of viral RNA-dependent RNA polymerase (RdRp). Upon entering infected cells, Favipiravir undergoes intracellular phosphorylation to form its active ribofuranosyl triphosphate metabolite. This active form competes with natural nucleotides during viral replication, leading to lethal mutagenesis and the eventual termination of the viral life cycle. Originally developed by Fujifilm Toyama Chemical Co., Ltd., the drug has gained widespread attention for its efficacy against various RNA viruses, including influenza A and B strains, Ebola virus, and notably, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).
In terms of therapeutic applications, Favipiravir is primarily indicated for the treatment of novel or re-emerging infectious diseases when no approved alternatives exist. It has been authorized for emergency use in several countries, particularly Japan and China, for managing moderate to severe cases of influenza and COVID-19. The drug is typically administered orally in tablet form, offering a convenient route for patients compared to intravenous therapies. While generally well-tolerated, common side effects may include gastrointestinal disturbances and elevated uric acid levels. Ongoing research continues to explore its potential in treating other emerging viral threats, solidifying its role as a critical component in global pandemic preparedness strategies. As a versatile antiviral, Favipiravir represents a vital tool in modern pharmacology for combating rapidly evolving viral pathogens.
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