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Basic Info
CAS Number
518-17-2
Pharmacopoeia
In-house Standards
Grade
food grade, pharmaceutical grade
Is Manufacturer
YES
Product Description
Evodia rutaecarpa alkali jianwei, analgesia, check the dry heaves and check oxyrygmia etc;
Have a diuretic effect;
Strong inhibitory effect on e. coli
There is a significant to the pig tapeworm insecticidal effect;
Was the contraction of uterus and booster function.
Treatment of alzheimer's disease and stroke have certain curative effect palm red to white powder.
AI Product Description
*The following content is generated by AI and is for reference only.
Evodiamine is a potent bioactive alkaloid primarily isolated from the dried fruit of *Evodia rutaecarpa*, commonly known as Wu Zhu Yu in traditional Chinese medicine. Its chemical identity is defined by the molecular formula C19H16N2O and the CAS registry number 6450-37-5. Structurally, it belongs to the quinolone alkaloid family, characterized by a unique tetracyclic skeleton that contributes significantly to its diverse pharmacological activities. This compound has garnered substantial attention in modern scientific research due to its multifaceted therapeutic potential, particularly in the fields of oncology, metabolism, and cardiovascular health.
In preclinical studies, Evodiamine has demonstrated remarkable anti-cancer properties by inducing apoptosis in various tumor cell lines, including breast, liver, and lung cancers. It functions by disrupting mitochondrial membrane potential and inhibiting key signaling pathways such as PI3K/Akt and MAPK, thereby suppressing tumor proliferation and metastasis without causing significant toxicity to normal cells. Beyond its anti-neoplastic effects, this molecule exhibits promising metabolic benefits. Research indicates that Evodiamine can activate AMP-activated protein kinase (AMPK), leading to enhanced lipid oxidation and improved insulin sensitivity. These mechanisms suggest its utility in managing obesity and type 2 diabetes by promoting energy expenditure and reducing adipose tissue accumulation.
Furthermore, Evodiamine possesses notable anti-inflammatory and analgesic capabilities, aligning with its historical use in treating headaches and gastrointestinal disorders within traditional medical systems. Its ability to modulate inflammatory cytokines makes it a candidate for treating chronic inflammatory conditions. Currently, while most applications remain in the experimental or clinical trial phases, Evodiamine serves as a valuable lead compound for drug discovery. Researchers are actively investigating its derivatives to improve bioavailability and reduce side effects. As a natural product with a well-documented safety profile in traditional contexts, Evodiamine represents a bridge between ancient herbal wisdom and contemporary pharmaceutical innovation, offering hope for novel treatments against complex metabolic and malignant diseases.
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