Product Description
Ethynyl estradiol USP Hormone API made in china 57-63-6
AI Product Description
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Ethynyl estradiol, designated as the United States Pharmacopeia (USP) grade Hormone Active Pharmaceutical Ingredient (API), is a potent synthetic estrogen widely manufactured in China for global pharmaceutical distribution. Chemically known as 17α-ethinylestradiol, its molecular formula is C₂₀H₂₄O₂, and it carries the CAS Registry Number 57-63-6. This compound represents a cornerstone in modern endocrinology and reproductive medicine due to its exceptional oral bioavailability and high affinity for estrogen receptors compared to natural estradiol.
The primary application of Ethynyl estradiol USP lies in hormonal contraception. It serves as a critical component in combined oral contraceptive pills, working synergistically with progestins to inhibit ovulation, thicken cervical mucus, and alter the endometrium to prevent pregnancy. Beyond family planning, this API is extensively utilized in hormone replacement therapy (HRT) for managing menopausal symptoms such as hot flashes, vaginal atrophy, and mood disturbances in postmenopausal women. Additionally, it plays a role in treating certain gynecological disorders, including dysmenorrhea and abnormal uterine bleeding, by regulating hormonal imbalances.
Manufactured under strict Good Manufacturing Practices (GMP) in China, the USP-grade Ethynyl estradiol ensures high purity, typically exceeding 98%, meeting rigorous international quality standards for safety and efficacy. The production process involves sophisticated chemical synthesis to achieve the specific stereochemistry required for biological activity. As a key intermediate in the global pharmaceutical supply chain, Chinese manufacturers provide this API to formulators worldwide, supporting the production of tablets, injectables, and transdermal patches. Its stability and predictable pharmacokinetic profile make it indispensable for ensuring consistent therapeutic outcomes. Consequently, Ethynyl estradiol remains a vital molecule in addressing female health needs, bridging the gap between advanced chemical manufacturing and essential clinical care across diverse medical landscapes globally.