Product Description
Erythromycin stearate BP 98%min supplier Pharmaceutical API Antibiotic GMP made in china 643-22-1
AI Product Description
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Erythromycin Stearate is a widely utilized semi-synthetic macrolide antibiotic derived from the fermentation of *Saccharomyces* species, specifically formulated as the stearate salt to enhance stability and bioavailability. Produced in compliance with strict British Pharmacopoeia (BP) standards requiring a minimum purity of 98%, this high-grade pharmaceutical API is manufactured by leading Chinese suppliers adhering to Good Manufacturing Practice (GMP) regulations. Its chemical identity is defined by the molecular formula C37H67NO13 and the CAS Registry Number 1264-62-6. Structurally, it consists of erythromycin linked to stearic acid, creating a stable crystalline powder that is practically insoluble in water but soluble in organic solvents like ethanol and chloroform.
The primary therapeutic application of Erythromycin Stearate lies in its broad-spectrum antibacterial activity against Gram-positive organisms, including streptococci, pneumococci, and staphylococci, as well as certain atypical pathogens such as *Mycoplasma pneumoniae*, *Chlamydia trachomatis*, and *Legionella*. It functions by inhibiting bacterial protein synthesis through reversible binding to the 50S ribosomal subunit, effectively halting peptide chain elongation. Clinically, it serves as a vital alternative for patients allergic to penicillin and is frequently prescribed for respiratory tract infections, skin and soft tissue infections, pertussis, and chlamydial infections. The stearate form is particularly favored in oral dosage forms, such as tablets and capsules, due to its reduced gastric irritation compared to the base form and improved shelf-life characteristics.
Global pharmaceutical supply chains rely heavily on Chinese manufacturers for this compound, ensuring consistent quality and cost-effectiveness for international markets. The product undergoes rigorous testing for potency, impurity profiles, and microbial limits to meet BP specifications. Beyond human medicine, it finds niche applications in veterinary formulations for treating similar infections in livestock and poultry. As a cornerstone macrolide antibiotic, Erythromycin Stearate remains an essential component of global antimicrobial stewardship programs, offering a reliable treatment option for a diverse range of bacterial infections while maintaining high safety standards through advanced GMP-controlled production processes.