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CAS NO:
57-87-4
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Basic Info
CAS Number
57-87-4
Pharmacopoeia
In-house Standards
Grade
Pharmaceutical Grade
Is Manufacturer
No
Product Description
please call me ,to know more
AI Product Description
*The following content is generated by AI and is for reference only.
Ergosterol, chemically known as (5Z,7E)-(24R)-ergosta-5,7,22-trien-3β-ol, is a vital sterol found predominantly in fungi, yeasts, and certain protozoa. It serves as the primary precursor to vitamin D2 (cholecalciferol) upon exposure to ultraviolet light, playing a crucial role in the biological synthesis of this essential nutrient. Structurally, ergosterol possesses a unique conjugated diene system within its B-ring, which distinguishes it from cholesterol, the major sterol in animal cells. Its molecular formula is C28H44O, with a precise molecular weight of approximately 396.64 g/mol. The standard CAS registry number for this compound is 57-87-4.
In the pharmaceutical and biotechnology sectors, ergosterol is extensively utilized as a reference standard for analytical chemistry and quality control. Because it is absent in mammalian tissues, it acts as a specific biomarker for fungal contamination in food, beverages, and industrial processes. Researchers employ high-performance liquid chromatography (HPLC) and gas chromatography-mass spectrometry (GC-MS) to quantify ergosterol levels, thereby assessing microbial load without relying on traditional culture methods. Furthermore, its conversion into vitamin D2 makes it a key ingredient in the production of dietary supplements and fortified foods, particularly for vegan populations seeking non-animal sources of the vitamin.
Beyond nutrition, ergosterol has significant applications in cell biology research. Scientists use it to study membrane fluidity and permeability, as it mimics the structural function of cholesterol in fungal cell membranes. This property also renders it a target for antifungal drug development; many azole-based antifungals work by inhibiting enzymes responsible for ergosterol biosynthesis, effectively disrupting the integrity of the fungal cell wall. Additionally, it is used in the formulation of liposomes and other lipid-based delivery systems due to its stability and solubility characteristics. As a natural product, ergosterol remains indispensable in both academic research and industrial applications, bridging the gap between fundamental mycology and practical therapeutic solutions. Its unique chemical profile ensures its continued relevance in advancing our understanding of fungal physiology and developing effective treatments against fungal infections.
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