Product Description
Appearance White crystals or crystalline powder Conforms
Specific Rotation -0.05o to +0.05o Conforms
Loss on drying Not more than 1.0% 0.5%
Assay Not less than 98.0% 98.9%
AI Product Description
*The following content is generated by AI and is for reference only.
DL-Serine Hydrazide Hydrochloride is a specialized amino acid derivative widely utilized in the fields of organic synthesis, medicinal chemistry, and biochemical research. With the CAS Registry Number 15632-74-9, this compound serves as a crucial building block for constructing complex heterocyclic structures and peptide analogs. Its molecular formula is C₃H₉ClN₂O₂, reflecting its composition of serine modified with a hydrazide functional group and stabilized by a hydrochloride salt form, which ensures high solubility in aqueous media and improved handling stability compared to the free base.
The primary application of DL-serine hydrazide hydrochloride lies in the synthesis of bioactive molecules. Researchers frequently employ it as a key intermediate for preparing pyrazoles, triazoles, and other nitrogen-containing rings that are prevalent in pharmaceutical agents. These heterocycles often exhibit significant biological activities, including antimicrobial, antifungal, and anticancer properties. Furthermore, this reagent plays an essential role in solid-phase peptide synthesis and the modification of proteins, where the hydrazide moiety allows for selective coupling reactions or the formation of stable linkages in drug delivery systems.
In academic laboratories, the compound is also valued for studying enzyme mechanisms involving serine residues, particularly in protease inhibition studies. The hydrochloride salt form facilitates precise stoichiometric control during reaction setups, minimizing side reactions associated with moisture sensitivity. Due to its chiral nature (being a racemic mixture of D and L enantiomers), it offers versatility for screening both stereoisomers to determine specific biological efficacy. As a versatile chemical tool, DL-serine hydrazide hydrochloride continues to support advancements in drug discovery and materials science, providing chemists with a reliable pathway to generate novel therapeutic candidates and functional biomaterials with high precision and efficiency.