Product Description
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AI Product Description
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Dipotassium Glycyrrhizinate is the dipotassium salt of glycyrrhizinic acid, a major bioactive triterpenoid saponin derived from the roots of *Glycyrrhiza glabra* (licorice). Its molecular formula is C42H60K2O16, and it carries the CAS Registry Number 3957-65-9. This white to off-white crystalline powder exhibits excellent water solubility, making it highly suitable for formulation in aqueous-based cosmetic and pharmaceutical products. Unlike its parent compound, glycyrrhizic acid, which can be unstable or less soluble, the dipotassium salt offers superior stability and enhanced skin penetration, facilitating more effective delivery of active ingredients.
The primary application of Dipotassium Glycyrrhizinate lies in the skincare industry, where it is widely recognized as a potent anti-inflammatory and soothing agent. It effectively alleviates skin irritation, redness, and sensitivity caused by environmental stressors, UV exposure, or harsh cosmetic formulations. By inhibiting the production of pro-inflammatory cytokines and suppressing phospholipase A2 activity, it helps calm irritated skin conditions such as eczema, dermatitis, and acne. Furthermore, it possesses mild antioxidant properties that protect skin cells from oxidative damage, contributing to overall skin health and barrier function.
Beyond cosmetics, this ingredient finds utility in oral care products due to its ability to reduce inflammation in the oral mucosa and freshen breath. In the pharmaceutical sector, it serves as an excipient or therapeutic agent for treating gastrointestinal ulcers and liver disorders, leveraging its hepatoprotective effects. Regulatory bodies in the United States, Europe, and Asia generally recognize it as safe for use in topical applications at specified concentrations. Its versatility allows formulators to include it in serums, creams, lotions, toners, and masks designed for sensitive or compromised skin types. As consumers increasingly seek gentle yet effective solutions for skin calming, Dipotassium Glycyrrhizinate remains a cornerstone ingredient in modern dermatological formulations, bridging traditional herbal wisdom with contemporary scientific standards to promote resilient, healthy skin.