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Basic Info
CAS Number
19057-60-4
Pharmacopoeia
In-house Standards
Grade
Pharmaceutical Grade
Is Manufacturer
YES
Product Description
- Cat. #: APC-094
- Product: Dioscin
- CAS No.: 19057-60-4
- Molecular Formula: C45H72O16
- Molecular Weight: 869.0436g/mol
- Specification: 98%min by HPLC
- Availability: Bulk and Research Quantity
AI Product Description
*The following content is generated by AI and is for reference only.
Dioscin is a naturally occurring steroidal saponin widely isolated from various plant species, most notably Dioscorea zingiberensis (Chinese yam) and Solanum species. With the chemical formula C27H42O10 and the CAS Registry Number 512-04-9, this compound belongs to the class of spirostane-type saponins. Its molecular structure features a characteristic spirostane skeleton with multiple hydroxyl groups, which contributes significantly to its biological activity and solubility profile in aqueous environments when complexed with surfactants or specific solvents.
In the pharmaceutical and biotechnological sectors, Dioscin is primarily valued for its diverse pharmacological properties. Extensive research indicates that it possesses potent anti-inflammatory, antioxidant, and antitumor activities. Specifically, studies have demonstrated its ability to induce apoptosis in various cancer cell lines, including hepatocellular carcinoma and breast cancer cells, often by modulating key signaling pathways such as PI3K/Akt and MAPK. Furthermore, Dioscin exhibits significant potential in managing metabolic disorders; it has been shown to improve insulin sensitivity and reduce lipid accumulation, making it a promising candidate for treating obesity and type 2 diabetes. Its immunomodulatory effects also suggest utility in enhancing host defense mechanisms against infections.
Beyond medicine, Dioscin serves as a crucial starting material in the semi-synthesis of other valuable steroid hormones and drugs, including corticosteroids and sex hormones. In agricultural applications, it acts as a natural pesticide due to its toxicity against certain pests and fungi, offering an eco-friendly alternative to synthetic chemicals. Additionally, researchers utilize Dioscin as a standard reference compound in analytical chemistry for quality control in herbal medicines containing Dioscorea extracts. Despite its benefits, the bioavailability of Dioscin remains a challenge due to poor water solubility, prompting ongoing investigations into novel delivery systems like nanoparticles and liposomes to enhance its therapeutic efficacy. As global interest in natural products grows, Dioscin continues to be a focal point for drug discovery and functional food development, bridging traditional herbal knowledge with modern scientific validation.
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