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CAS NO:
52328-98-0
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Basic Info
CAS Number
52328-98-0
Pharmacopoeia
In-house Standards
Grade
Pharmaceutical Grade
Is Manufacturer
No
Product Description
please call me ,to know more
AI Product Description
*The following content is generated by AI and is for reference only.
Dimethylcurcumin, chemically known as 1,7-bis(4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione, is a potent synthetic analog of the natural polyphenol curcumin derived from turmeric. With the molecular formula C21H20O5 and a CAS registry number of 89706-97-4, this compound represents a significant advancement in medicinal chemistry aimed at overcoming the bioavailability limitations inherent to its parent molecule. While curcumin exhibits remarkable anti-inflammatory, antioxidant, and anticancer properties, its poor aqueous solubility and rapid metabolic degradation often restrict its therapeutic efficacy. Dimethylcurcumin addresses these challenges through strategic methylation of specific hydroxyl groups, which enhances lipophilicity and metabolic stability without compromising biological activity.
The primary applications of dimethylcurcumin lie in pharmaceutical research and nutraceutical development, particularly for treating chronic inflammatory conditions, neurodegenerative disorders, and various malignancies. Studies suggest that it effectively inhibits key signaling pathways involved in inflammation, such as NF-kappaB, while scavenging free radicals more efficiently than standard curcumin. Furthermore, its improved pharmacokinetic profile allows for better tissue penetration, making it a promising candidate for drug delivery systems targeting the central nervous system and gastrointestinal tract. In cosmetic science, it is increasingly utilized for its skin-whitening and anti-aging capabilities due to its ability to suppress melanin production and protect against UV-induced oxidative stress.
Despite its advantages, ongoing clinical trials are necessary to fully validate its safety and dosage protocols for human use. As a derivative designed to optimize the pharmacological potential of natural products, dimethylcurcumin stands out as a vital tool in modern therapeutics. Researchers continue to explore its synergistic effects when combined with other agents, aiming to develop next-generation treatments for complex diseases where conventional therapies fall short. Its unique chemical structure offers a bridge between traditional herbal medicine and contemporary precision medicine, highlighting the enduring value of structural modification in drug discovery.
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