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Intermediates&Fine Chemicals

Difluoxacin hydrochloride

Category:

Intermediates&Fine Chemicals

CAS NO:

91296-86-5

Standard:

In-house Standards,

Price Range:

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North America,Central/South America,Western Europe,Eastern Europe,Australasia,Asia,Middle East,Africa

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INNER MONGOLIA YUANHONG FINE CHEMICAL CO., LTD.

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Basic Info

CAS Number

91296-86-5

Pharmacopoeia

In-house Standards

Grade

Pharmaceutical Grade

Is Manufacturer

Samples Provided

Product Description

Difluoxacin hydrochloride 91296-86-5

AI Product Description

*The following content is generated by AI and is for reference only.

Difloxacin hydrochloride is a synthetic fluoroquinolone antibiotic widely utilized in veterinary medicine for the treatment of bacterial infections in various animal species. Chemically, it is characterized by its specific molecular formula, C19H20F2N3O4·HCl, and carries the CAS Registry Number 115556-08-0. As a hydrochloride salt, difloxacin exhibits enhanced water solubility compared to its free base form, facilitating better absorption and bioavailability when administered orally or via injection. The drug functions by inhibiting bacterial DNA gyrase and topoisomerase IV, essential enzymes required for DNA replication, transcription, and repair, thereby exerting a potent bactericidal effect against a broad spectrum of Gram-positive and Gram-negative pathogens. Commonly indicated for treating respiratory tract infections, skin and soft tissue infections, and gastrointestinal disorders caused by susceptible bacteria such as *Staphylococcus*, *Streptococcus*, *E. coli*, and *Pasteurella* species, difloxacin is particularly valuable in livestock management, poultry farming, and companion animal care. Its efficacy extends to conditions like bovine respiratory disease, swine dysentery, and avian colibacillosis. Due to its pharmacokinetic profile, including long half-life and high tissue penetration, dosing regimens are often optimized for once-daily administration, improving compliance in clinical settings. However, strict adherence to withdrawal periods is mandatory before meat or milk products enter the food chain to prevent residues in human consumption. While generally well-tolerated, potential side effects may include gastrointestinal disturbances or transient elevation of liver enzymes. Regulatory bodies worldwide classify this compound under specific veterinary drug guidelines, emphasizing responsible use to mitigate the growing threat of antimicrobial resistance. Continuous monitoring of usage patterns remains critical to preserving the therapeutic efficacy of fluoroquinolones in modern veterinary practice.