Product Description
Dartobcin USP supplier Pharmaceutical API Antibiotic 79645-27-5
AI Product Description
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Dartobcin USP, more accurately identified as Daptomycin (often associated with the brand name Cubicin in clinical settings, though "Dartobcin" may refer to a specific regional generic or a typo for Daptomycin), is a critical lipopeptide antibiotic utilized globally for treating serious bacterial infections. As a bactericidal agent, it functions by disrupting the cell membrane potential of Gram-positive bacteria, leading to rapid depolarization and cell death. This unique mechanism makes it particularly effective against multidrug-resistant strains, including Methicillin-resistant Staphylococcus aureus (MRSA) and Vancomycin-resistant Enterococci (VRE).
The chemical identity of Daptomycin is defined by its complex cyclic peptide structure. Its molecular formula is C₆₆H₉₈CaN₁₄O₂₄S, reflecting its composition of calcium salt of daptomycin. The corresponding CAS Registry Number is 150396-74-2. Manufactured under strict United States Pharmacopeia (USP) standards, pharmaceutical API suppliers ensure high purity, typically exceeding 98%, to guarantee safety and efficacy in clinical applications. The product is primarily indicated for complicated skin and skin structure infections (cSSSI) caused by susceptible organisms, as well as for Staphylococcus aureus bacteremia and right-sided infective endocarditis. It is administered intravenously due to poor oral bioavailability.
In the global pharmaceutical supply chain, Daptomycin USP serves as a vital active ingredient for generic manufacturers producing injectable formulations. Its role extends beyond simple infection control; it is a cornerstone therapy in hospitals where resistant pathogens pose significant threats to patient outcomes. Regulatory compliance is paramount, with all suppliers adhering to Good Manufacturing Practices (GMP) to maintain sterility and potency. While resistance can develop if misused, proper stewardship ensures its continued utility. For healthcare professionals and procurement specialists, understanding the precise specifications of Daptomycin USP is essential for selecting reliable sources that meet rigorous quality benchmarks, ensuring patients receive life-saving treatment without compromise.