Dapagliflozin Propanediol Monohydrate CAS 960404-48-2
AI Product Description
*The following content is generated by AI and is for reference only.
<h3>Overview</h3>
<p>Dapagliflozin Propanediol Monohydrate (<strong>CAS 960404-48-2</strong>) is a crystalline salt form of the SGLT2 inhibitor Dapagliflozin, synthesized via controlled reaction with propanediol. This hydrate variant ensures superior stability and solubility for pharmaceutical manufacturing. Its molecular formula reflects the specific stoichiometric hydration essential for consistent API performance.</p>
<h3>Application</h3>
<ul>
<li>Pharmaceutical Manufacturing: Primary active ingredient for Type 2 Diabetes mellitus treatments.</li>
<li>Formulation Development: Used in tablet and capsule production to enhance bioavailability.</li>
<li>Quality Control: Serves as reference standard for purity verification in regulatory testing.</li>
</ul>
<h3>Precautions</h3>
<p>Store under dry conditions below 25°C to prevent deliquescence or hydrate loss. Personnel must utilize PPE including gloves and respirators during handling due to potential respiratory sensitization. Contraindicated in patients with severe renal impairment or history of hypersensitivity to SGLT2 inhibitors.</p>