Product Description
Cefuroxime sodium USP/BP 98%min supplier Pharmaceutical API Antibiotic 56238-63-2
AI Product Description
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Cefuroxime Sodium is a widely utilized second-generation cephalosporin antibiotic, renowned for its broad-spectrum efficacy against both Gram-positive and Gram-negative bacteria. Supplied in high-purity forms adhering to United States Pharmacopeia (USP) and British Pharmacopoeia (BP) standards with a minimum purity of 98%, this pharmaceutical active ingredient serves as a critical component in treating various bacterial infections. The molecular formula of Cefuroxime Sodium is C16H16N4NaO8S2, and it is uniquely identified by the CAS number 55313-80-5. Its chemical structure features a beta-lactam ring essential for inhibiting bacterial cell wall synthesis, thereby preventing replication and leading to bacterial cell death.
This antibiotic is particularly effective against pathogens resistant to first-generation cephalosporins, making it a preferred choice for respiratory tract infections, including pneumonia and bronchitis, as well as urinary tract infections, skin and soft tissue infections, and otitis media. It also demonstrates significant activity against *Haemophilus influenzae* and *Moraxella catarrhalis*, often used in cases of acute exacerbations of chronic bronchitis. In clinical settings, Cefuroxime Sodium is primarily administered via intravenous or intramuscular injection due to its poor oral bioavailability in the sodium salt form, although specific ester prodrugs exist for oral administration.
As a bulk pharmaceutical API, suppliers ensure strict quality control regarding stability, sterility, and endotoxin levels to meet global regulatory requirements. The product is extensively used in hospital formularies worldwide for empiric therapy before culture results are available. Its stability profile allows for versatile storage conditions, provided it is protected from moisture and light. By targeting penicillin-binding proteins, Cefuroxime Sodium offers a robust therapeutic option for patients with serious bacterial infections, balancing safety with potent antimicrobial activity. Consequently, it remains a cornerstone in modern antimicrobial stewardship programs, helping to combat the rising tide of antibiotic resistance through its reliable and predictable pharmacokinetic properties.