Product Description
Cefsulodine sodium antibiocs pharmaceutical supplier Diminish inflammation 52152-93-9
AI Product Description
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Cefsulodine sodium is a potent, broad-spectrum cephalosporin antibiotic specifically engineered for the treatment of severe infections caused by Pseudomonas aeruginosa and other multidrug-resistant Gram-negative bacteria. As a semi-synthetic derivative of cephalosporin C, it belongs to the third generation of cephalosporins but possesses unique characteristics that distinguish it from its peers, particularly regarding its stability against beta-lactamases produced by Pseudomonas species. The chemical identity of this compound is defined by its molecular formula, C17H15N3Na2O6S2, and it is registered under the CAS number 60986-45-4. It is supplied in its sodium salt form to ensure optimal solubility for intravenous or intramuscular administration in clinical settings.
The primary therapeutic application of Cefsulodine sodium lies in managing complicated urinary tract infections, septicemia, respiratory tract infections, and soft tissue infections where Pseudomonas aeruginosa is the suspected or confirmed pathogen. Its mechanism of action involves the inhibition of bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs), leading to cell lysis and death. While not primarily marketed as an anti-inflammatory agent, the rapid eradication of the underlying bacterial infection significantly reduces the inflammatory response associated with severe sepsis and tissue damage. By eliminating the source of inflammation, it facilitates patient recovery and prevents the progression of systemic complications. Pharmaceutical suppliers worldwide provide high-purity grades of Cefsulodine sodium for both research purposes and clinical manufacturing, ensuring compliance with international quality standards such as GMP. Despite its efficacy, usage requires careful monitoring due to potential side effects like gastrointestinal disturbances, hypersensitivity reactions, or transient elevations in liver enzymes. Clinicians must consider allergy history, particularly regarding beta-lactams, before prescribing. Overall, Cefsulodine sodium remains a critical tool in modern antimicrobial therapy, offering a vital defense against resistant pathogens when other antibiotics fail.