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Carbetocin supplier Pharmaceutical API Polypeptide made in china

Category:

Intermediates&Fine Chemicals

CAS NO:

37025-55-1

Standard:

In-house Standards,

Price Range:

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Main Sales Markets:

North America,Central/South America,Western Europe,Eastern Europe,Australasia,Asia,Middle East,Africa

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INNER MONGOLIA YUANHONG FINE CHEMICAL CO., LTD.

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Basic Info

CAS Number

37025-55-1

Pharmacopoeia

In-house Standards

Grade

Pharmaceutical Grade

Is Manufacturer

Samples Provided

Product Description

Carbetocin supplier Pharmaceutical API Polypeptide made in china 37025-55-1

AI Product Description

*The following content is generated by AI and is for reference only.

Carbetocin, a synthetic analog of oxytocin, is a critical polypeptide active pharmaceutical ingredient (API) widely manufactured in China for global distribution. Its molecular formula is C46H69N15O13S2, with a molecular weight of approximately 1047.2 g/mol. The substance is identified by the CAS number 81133-37-7. Structurally, Carbetocin differs from natural oxytocin by the substitution of the amide group at position 3 with an N-methyl-L-glutamine residue and the replacement of the C-terminal glycine amide with an ethylamide group. These modifications significantly extend its half-life, allowing for prolonged uterine contraction without the need for repeated dosing. The primary clinical application of Carbetocin is the prevention and treatment of postpartum hemorrhage (PPH), a leading cause of maternal mortality worldwide. It acts as a potent uterotonic agent by binding to oxytocin receptors on the myometrium, inducing strong, rhythmic contractions that compress blood vessels at the placental site. Due to its long duration of action, typically lasting up to four hours after a single intravenous or subcutaneous injection, it offers a distinct advantage over oxytocin, which requires continuous infusion and has a very short half-life. This pharmacokinetic profile makes it particularly suitable for cesarean sections and vaginal deliveries where immediate and sustained hemostasis is required. China serves as a major hub for the production of high-quality Carbetocin API, leveraging advanced peptide synthesis technologies and rigorous Good Manufacturing Practice (GMP) standards. Suppliers in this region provide bulk quantities to international pharmaceutical companies, ensuring a stable supply chain for essential obstetric medications. The product is available in various formulations, including lyophilized powders for reconstitution, catering to diverse hospital settings globally. As a non-glycosylated decapeptide, Carbetocin represents a significant advancement in obstetric care, balancing efficacy with patient safety. Its widespread adoption underscores its role in reducing PPH-related complications, making it a staple in modern maternity wards across Europe, Asia, and the Americas.