For umbrelliferae plant radix bupleuri BupleurumchinenseDC. (xi said: bupleurum chinense) root powder extract products.
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Bupleurum Extract is a widely utilized herbal preparation derived primarily from the dried roots of *Bupleurum chinense* DC. or *Bupleurum scorzonerifolium* Willd., plants belonging to the Apiaceae family and renowned in Traditional Chinese Medicine (TCM) for their ability to soothe the liver and resolve depression. The extract is rich in bioactive compounds, with saikosaponins serving as the primary active constituents responsible for its therapeutic efficacy. While specific molecular formulas vary depending on the individual saponin type isolated—such as Saikosaponin A (C41H68O13), Saikosaponin D (C42H68O13), or Saikosaponin F (C42H68O14)—there is no single universal CAS number for the crude extract itself; rather, distinct CAS numbers apply to each purified component, typically ranging between 507-90-4 and 21343-63-5.
Functionally, Bupleurum Extract is celebrated for its broad-spectrum pharmacological activities. It exhibits potent anti-inflammatory properties by inhibiting pro-inflammatory cytokines like TNF-alpha and IL-6, making it valuable in managing chronic inflammatory conditions. Furthermore, the extract demonstrates significant hepatoprotective effects, aiding in the regeneration of liver cells and protecting against toxins induced by alcohol or drugs. Its immunomodulatory capabilities help regulate immune responses, while antiviral studies suggest potential utility against influenza viruses and hepatitis. In clinical practice and dietary supplements, this extract is frequently employed to treat symptoms associated with liver dysfunction, such as jaundice, hypochondriac pain, and fever, as well as to alleviate emotional stress and menstrual irregularities linked to liver qi stagnation. Modern pharmaceutical applications often incorporate standardized extracts into formulations targeting metabolic disorders and autoimmune diseases. The extraction process usually involves ethanol or water methods to maximize the yield of saponins and flavonoids. As a natural alternative to synthetic drugs, Bupleurum Extract offers a safe profile when used according to established guidelines, though dosage precision remains critical to avoid adverse interactions. Its versatility continues to drive research into new therapeutic avenues within integrative medicine.