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Plant Extracts
CAS NO:
84776-26-1
Standard:
ChP,USP,BP,EP,In-house Standards,
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Basic Info
CAS Number
84776-26-1
Pharmacopoeia
ChP,USP,BP,EP,In-house Standards
Grade
Food Grade
Is Manufacturer
YES
Packaging & Delivery
Packaging Specification
1kg/bag 25kg/drum
Minimum Order Quantity
25KG
Delivery Cycle
3 working days
Product Description
We are professional Raw Material Manufacturer, with more than 10 years' experience.
Please contact us for more information and detailed quotation
Email: sales12@sgonekbio.com
Phone/WhatsApp/Wechat: +86 13572550462
AI Product Description
*The following content is generated by AI and is for reference only.
Black cohosh extract, derived from the roots and rhizomes of *Actaea racemosa* (formerly *Cimicifuga racemosa*), is a widely utilized botanical supplement known primarily for its potential to alleviate menopausal symptoms. Unlike many herbal products that rely on estrogenic activity, black cohosh appears to function through non-hormonal mechanisms, possibly involving serotonin receptors or modulation of the hypothalamic-pituitary axis. The specific chemical composition varies depending on extraction methods, but key bioactive constituents include triterpene glycosides such as actein, cimicifugoside, and 23-epi-26-deoxyactein. Notably, the exact molecular formula cannot be assigned to the "extract" as a single entity because it is a complex mixture of multiple compounds rather than a pure substance; however, individual active markers like actein have distinct molecular structures. Consequently, there is no single CAS number for the crude extract itself. Instead, manufacturers often reference CAS numbers for specific standardized components, such as CAS 18794-05-1 for actein or CAS 139755-78-3 for other glycosides.
The primary clinical application of black cohosh extract centers on managing vasomotor symptoms associated with menopause, including hot flashes, night sweats, and sleep disturbances. It is also frequently used to address mood swings, anxiety, and joint pain experienced during this transitional life stage. While some studies suggest benefits for premenstrual syndrome and uterine health, robust scientific consensus remains focused on menopausal relief. Safety profiles generally indicate short-term use is well-tolerated, though rare cases of hepatotoxicity have been reported, necessitating caution in individuals with liver conditions. Regulatory bodies classify it as a dietary supplement rather than a pharmaceutical drug, meaning product quality and concentration can vary significantly between brands. Consumers are advised to look for extracts standardized to specific triterpene content to ensure efficacy. Despite its long history in traditional Native American medicine and European phytotherapy, ongoing research continues to explore its precise molecular pathways and long-term safety. Overall, black cohosh remains a popular natural alternative for women seeking hormone-free symptom management, provided it is sourced from reputable manufacturers adhering to Good Manufacturing Practices.
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