N,O-Bis(trimethylsilyl) trifluoroacetamide is an important pharmaceutical intermediate that can reduce the polarity of hydroxyl-containing compounds, increase their volatility, and make samples more suitable for GC analysis. Mainly used as a neutral silanization reagent Chemicalbook in the silanization protection of amino groups, amino acids, phenols, carboxylic acids and enols, as a mild neutral silanization reagent, not only high reactivity, good selectivity, but also has the advantages of high reaction yield and simple post-treatment.