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*The following content is generated by AI and is for reference only.
Concanavalin A (ConA) extract, often marketed under various trade names including "Best Price Concanavax Extract," is a potent lectin derived from the jack bean (*Canavalia ensiformis*). While the specific commercial product name "Concanavax" may be a proprietary or historical branding variation, the active constituent remains Concanavalin A. It is important to clarify that ConA is a protein complex rather than a small molecule; therefore, it does not possess a single molecular formula or a traditional CAS number in the same manner as synthetic chemicals. Instead, the protein itself is identified by CAS Registry Number 9013-28-5. Its molecular weight varies depending on the oligomeric state, typically existing as a tetramer with an approximate mass of 104 kDa, composed of four identical subunits each containing about 267 amino acids.
The primary utility of Concanavalin A lies in its ability to bind specifically to alpha-D-mannose and alpha-D-glucose residues. This unique carbohydrate-binding property makes it an indispensable tool in biochemistry and immunology research. Scientists widely utilize ConA for cell separation, particularly in isolating T-lymphocytes, as it induces agglutination of these cells. Furthermore, it serves as a powerful mitogen, stimulating lymphocyte proliferation, which is critical for studying immune system responses and cell cycle regulation. In structural biology, ConA is frequently employed in affinity chromatography to purify glycoproteins and investigate their sugar moieties. The "Best Price" designation suggests a cost-effective formulation intended for laboratory use, offering high purity suitable for electrophoresis, Western blotting, and enzyme-linked assays. Despite its biological activity, handling requires care as it can induce strong immune reactions in sensitive individuals. Overall, Concanavalin A extract remains a foundational reagent for understanding glycosylation patterns and cellular interactions, bridging the gap between basic carbohydrate chemistry and complex immunological mechanisms in modern scientific inquiry.