Product Description
Berberine chloride hydrate CP2010/ JP13 API Pharmaceutical made in china 141433-60-5
AI Product Description
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Berberine chloride hydrate, a purified active pharmaceutical ingredient (API) manufactured in China according to strict standards such as the Chinese Pharmacopoeia 2010 (CP2010) and Japanese Pharmacopoeia 13th Edition (JP13), is a significant isoquinoline alkaloid derivative. Chemically known as Berberine chloride monohydrate, its molecular formula is C20H18ClNO4·H2O, with the specific CAS registry number 633-65-8. This bright yellow crystalline powder is highly soluble in water and exhibits strong antibacterial, antifungal, and anti-inflammatory properties.
Primarily utilized in traditional medicine and modern therapeutic research, Berberine chloride hydrate serves as a potent metabolic regulator. It is widely recognized for its ability to activate AMP-activated protein kinase (AMPK), a key enzyme involved in cellular energy homeostasis. Consequently, it plays a crucial role in managing type 2 diabetes by improving insulin sensitivity and reducing hepatic glucose production. Furthermore, clinical applications extend to lipid metabolism disorders, where it effectively lowers total cholesterol and triglyceride levels, offering a natural alternative to synthetic statins. The compound also demonstrates efficacy against various gastrointestinal infections, including those caused by *E. coli* and *Salmonella*, making it a valuable component in treating dysentery and diarrhea.
In the pharmaceutical industry, this API is formulated into tablets, capsules, and injectable solutions. Its compliance with CP2010 and JP13 ensures high purity, typically exceeding 98%, guaranteeing safety and efficacy for global markets. While generally well-tolerated, potential side effects may include mild gastrointestinal discomfort. Ongoing research continues to explore its potential in cancer therapy and neuroprotection. As a cost-effective, high-quality API sourced from Chinese manufacturers, Berberine chloride hydrate remains a cornerstone in the development of natural-based drugs for metabolic and infectious diseases worldwide.